Rabinowitz R, Barkin M, Schillinger J F, Jeffs R D, Cook G T
J Urol. 1979 Sep;122(3):370-2. doi: 10.1016/s0022-5347(17)56414-9.
Of 105 boys with posterior urethral valves managed during a 10-year period most were managed by primary valve ablation. However, 39 of these boys required concomitant or additional procedures to 71 massively dilated ureters because of azotemia, infection and/or progressive upper tract deterioration. In 17 boys 25 ureters could be reconstructed primarily by varying degrees of ureteral tailoring. When there was severe infection, azotemia and/or doubt as to the function of the affected renal unit, staged reconstruction was initiated by cutaneous ureterostomy. One-fourth of these ureterostomy diverted children died of azotemia despite free urinary drainage. Those who went on to have staged reconstruction, despite multiple surgical procedures, retained intact urinary systems with acceptable function.
在10年期间接受治疗的105例后尿道瓣膜症男孩中,大多数接受了一期瓣膜切除术。然而,这些男孩中有39例因氮质血症、感染和/或上尿路进行性恶化,需要对71条重度扩张的输尿管进行联合或额外手术。17例男孩的25条输尿管可通过不同程度的输尿管裁剪进行一期重建。当存在严重感染、氮质血症和/或对受影响肾单位功能存在疑问时,通过皮肤输尿管造口术开始分期重建。尽管尿液引流顺畅,但这些接受输尿管造口术分流的儿童中有四分之一死于氮质血症。那些继续接受分期重建的患者,尽管经历了多次外科手术,但仍保留了功能可接受的完整泌尿系统。