麻醉品成瘾者中的革兰氏阴性菌性心内膜炎。
Gram-negative bacterial endocarditis in narcotic addicts.
作者信息
Rosenblatt J E, Dahlgren J G, Fishbach R S, Tally F P
出版信息
Calif Med. 1973 Feb;118(2):1-4.
Abstract
The number of cases of bacterial endocarditis in drug addicts seen at UCLA and Wadsworth Veterans Administration hospitals increased sharply in 1971 over the average of the four preceding years. Enteric Gram-negative bacilli were the infecting organism in three of the seven cases seen in 1971 but were not found in any cases of endocarditis in the 1967-70 period. Medical treatment of the patients was, in general, unsuccessful in spite of the intensive use of newer antimicrobials active against enteric Gram-negative bacilli. One patient died with fulminant Pseudomonas endocarditis and two others (Pseudomonas and Serratia endocarditis) eventually required operations on the heart before a cure was achieved.
摘要
1971年，加利福尼亚大学洛杉矶分校（UCLA）和沃兹沃思退伍军人管理局医院收治的吸毒者细菌性心内膜炎病例数相比前四年的平均水平大幅增加。1971年所见的7例病例中有3例感染病原体为肠道革兰氏阴性杆菌，但在1967 - 1970年期间的心内膜炎病例中未发现此类病原体。尽管大量使用了对肠道革兰氏阴性杆菌有效的新型抗菌药物，但总体而言，对这些患者的药物治疗并不成功。一名患者死于暴发性假单胞菌性心内膜炎，另外两名患者（分别为假单胞菌性和沙雷氏菌性心内膜炎）最终在治愈前需要进行心脏手术。
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