普萘洛尔用于小儿室上性心动过速
Propranolol in supraventricular tachycardias of childhood.
作者信息
Dworkin P H, Bell B B, Mirowski M
出版信息
Arch Dis Child. 1973 May;48(5):382-5. doi: 10.1136/adc.48.5.382.
Abstract
9 children with supraventricular tachycardias refractory to conventional therapy were treated with propranolol. In 3 children normal sinus rhythm was restored. In 3 others frequency of paroxysmal arrhythmias was decreased. In 1 reduction of ventricular response to the ectopic rhythm was achieved, and in 2 remaining patients, propranolol had no effect. The dosage of propranolol ranged from 0·5 to 4·0 mg/kg per day, given orally, with few side effects. It appears that propranolol can play an important role in treatment of supraventricular arrhythmias of childhood unresponsive to conventional therapy.
摘要
9名患有对传统疗法难治的室上性心动过速的儿童接受了普萘洛尔治疗。3名儿童恢复了正常窦性心律。另外3名儿童阵发性心律失常的频率降低。1名儿童实现了心室对异位心律反应的降低，在其余2名患者中，普萘洛尔无效。普萘洛尔的剂量为每天0·5至4·0毫克/千克，口服，副作用很少。看来普萘洛尔在治疗对传统疗法无反应的儿童室上性心律失常中可以发挥重要作用。
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