链球菌性咽炎的治疗。I. 临床评估。
Treatment of streptococcal pharyngitis. I. Clinical evaluation.
作者信息
Rabinovitch M, MacKenzie R, Brazeau M, Marks M I
出版信息
Can Med Assoc J. 1973 May 19;108(10):1271-4.
Abstract
A study was undertaken to evaluate the therapy of streptococcal pharyngitis. The compliance of 118 patients with beta-hemolytic streptococcal pharyngitis to follow-up was 72%. Of 74 patients checked by means of urine tests 66 took their oral medication. No differences were detected in the clinical and bacteriological results (>98% streptococcal eradication) after the 7th or 10th day of therapy after taking either cephalexin or penicillin.IT WAS CONCLUDED THAT: (a) for effective surveillance and follow-up special attention should be given to the uncooperative segment of the patient population; (b) a seven-day course of penicillin may be satisfactory in the eradication of BHS from the throat; and (c) cephalexin appears to be an effective alternative to penicillin for the treatment of streptococcal pharyngitis.
摘要
开展了一项研究以评估链球菌性咽炎的治疗方法。118例β-溶血性链球菌性咽炎患者的随访依从率为72%。在通过尿液检测检查的74例患者中，66例服用了口服药物。服用头孢氨苄或青霉素治疗7天或10天后，临床和细菌学结果（链球菌根除率>98%）未发现差异。得出以下结论：(a) 为了进行有效的监测和随访，应特别关注患者群体中不合作的部分；(b) 青霉素的七天疗程在根除咽喉部的BHS方面可能是令人满意的；(c) 头孢氨苄似乎是治疗链球菌性咽炎的一种有效的青霉素替代药物。
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