MacGregor G A, Jones N F, Barraclough M A, Wing A J, Cranston W I
Br Med J. 1973 May 5;2(5861):271-2. doi: 10.1136/bmj.2.5861.271.
Three patients with analgesic nephropathy are reported who, in addition to the accepted features of this syndrome, had dilatation of one or both upper urinary tracts due to ureteric or periureteric fibrosis without intraluminal obstruction. We attribute this lesion to analgesic abuse and suggest that any patient with unexplained ureteric fibrosis should be questioned about analgesic consumption. This association also suggests a possible role for analgesic abuse in the pathogenesis of retroperitoneal fibrosis.
报告了3例镇痛剂肾病患者，除了该综合征公认的特征外，由于输尿管或输尿管周围纤维化而无腔内梗阻，导致一侧或双侧上尿路扩张。我们将此病变归因于镇痛剂滥用，并建议对任何原因不明的输尿管纤维化患者询问其镇痛剂使用情况。这种关联还提示镇痛剂滥用在腹膜后纤维化发病机制中可能起作用。
