Coria M F
Arch Gesamte Virusforsch. 1973;41(1):66-70. doi: 10.1007/BF01249930.
The antigenicity and protective effect of 3 strains of avian infectious bronchitis virus inactivated by beta-propiolactone were studied. Chickens administered 2 doses of the inactivated Connecticut strain (IBV-46) vaccine by aerosol at 3-week intervals had significant levels of virus-neutralizing antibodies and were resistant to infection by the Massachusetts strain (IBV-41) as determined by virus isolation attempts. Antibody levels in chickens given inactivated Iowa 33 and Iowa 609 were not significant and they were not resistant to infection by IBV-41.
研究了经β-丙内酯灭活的3株禽传染性支气管炎病毒的抗原性和保护作用。以3周的间隔通过气溶胶给鸡接种2剂灭活的康涅狄格毒株（IBV-46）疫苗后，鸡体内产生了显著水平的病毒中和抗体，并且通过病毒分离试验确定，这些鸡对马萨诸塞毒株（IBV-41）的感染具有抵抗力。接种灭活的爱荷华33株和爱荷华609株疫苗的鸡的抗体水平不显著，并且它们对IBV-41的感染没有抵抗力。
