Robinson R E
Postgrad Med J. 1979 May;55(643):358-61. doi: 10.1136/pgmj.55.643.358.
The introduction of insulin produced a rapid improvement in the maternal prognosis in pregnancy associated with diabetes mellitus. Within years, maternal mortality fell from 50% and has become a rarity. Improvement in fetal survival was less dramatic until the work of Pedersen (1952); Peel and Oakley (1950) and White (1949) demonstrated that with determined antenatal control of diabetes the fetal outcome was greatly improved. Further improvement in the care of the fetus of the pregnant diabetic with fetal monitoring, both ante- and intra-partum, together with modern neonatal expertise, had brought the perinatal and neonatal morbidity and mortality for this group of patients close to that of the non-diabetic. An account is given of the author's present day practice in this group of patients.
胰岛素的引入使糖尿病合并妊娠的孕产妇预后迅速得到改善。数年内，孕产妇死亡率从50%降至如今已很罕见的水平。在佩德森（1952年）开展相关工作之前，胎儿存活率的改善并不显著；皮尔和奥克利（1950年）以及怀特（1949年）证明，通过对糖尿病进行坚定的产前控制，胎儿结局得到了极大改善。对妊娠糖尿病孕妇的胎儿护理进一步改善，包括产前和产时的胎儿监测，以及现代新生儿专业技术，已使这类患者的围产期和新生儿发病率及死亡率接近非糖尿病患者。文中介绍了作者目前对这类患者的治疗方法。
