Taylor A, Marks V
Br J Ind Med. 1973 Jul;30(3):293-6. doi: 10.1136/oem.30.3.293.
293-296. Excretion of mercury was measured by a cold-vapour atomic absorption technique on samples of urine from five groups of people having varying exposure to mercury. Serial investigations of up to 14 days were carried out on eight subjects to determine the temporal relationship between exposure and excretion. Subjects with no exposure excreted 0-10 μg mercury per gramme creatinine. Similar values were found in laboratory staff and men assembling hollow cathode lamps. Excretion of mercury by dental workers was significantly increased. No correlation between exposure and excretion of mercury was seen in the subjects investigated. The significance of measuring urinary excretion in the detection of mercury intoxication is discussed. The suggestion is made that urinary mercury excretion of more than 20 μg/g creatinine or 40 μg mercury per 24 hours should be considered evidence of recent or remote exposure to mercury. It is concluded that measurement of urinary mercury excretion is important in revealing those persons who may ultimately develop symptoms of toxicity.
293 - 296。采用冷蒸汽原子吸收技术对五组汞暴露程度不同的人群的尿液样本进行汞排泄量测定。对八名受试者进行了长达14天的连续调查，以确定暴露与排泄之间的时间关系。未接触汞的受试者每克肌酐排泄0 - 10微克汞。在实验室工作人员和组装空心阴极灯的男性中也发现了类似的值。牙科工作人员的汞排泄量显著增加。在所调查的受试者中，未发现汞暴露与排泄之间存在相关性。讨论了测量尿排泄量在汞中毒检测中的意义。有人提出，每克肌酐尿汞排泄量超过20微克或每24小时排泄40微克汞应被视为近期或既往汞暴露的证据。得出的结论是，测量尿汞排泄量对于发现那些最终可能出现中毒症状的人很重要。
