Schedule-dependent therapeutic synergism for L-asparaginase and methotrexate in leukemic (L5178Y) mice.

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作者信息

Vadlamudi S, Krishna B, Reddy V V, Goldin A

出版信息

Cancer Res. 1973 Sep;33(9):2014-9.

PMID:4725366

Abstract

摘要

相似文献

Schedule-dependent therapeutic synergism for L-asparaginase and methotrexate in leukemic (L5178Y) mice.

Cancer Res. 1973 Sep;33(9):2014-9.

Factors influencing the therapeutic activity of L-asparaginase (NSC 109229) in leukemic (L5178Y) mice.

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Schedule-dependent synergy and antagonism between high-dose 1-beta-D-arabinofuranosylcytosine and asparaginase in the L5178Y murine leukemia.大剂量1-β-D-阿拉伯呋喃糖基胞嘧啶与天冬酰胺酶在L5178Y小鼠白血病中存在的时间依赖性协同作用和拮抗作用

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Asparaginase-methotrexate in combination chemotherapy: schedule-dependent differential effects on normal versus neoplastic cells.天冬酰胺酶-甲氨蝶呤联合化疗：对正常细胞与肿瘤细胞的给药方案依赖性差异效应

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L-asparaginase induced alteration of amethopterin (methotrexate) activity in mouse leukemia L5178Y.L-天冬酰胺酶诱导小鼠白血病L5178Y中氨甲蝶呤（甲氨蝶呤）活性的改变。

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Unresolved issues in combination chemotherapy.

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L-asparaginase-induced modulation of methotrexate polyglutamylation in murine leukemia L5178Y.L-天冬酰胺酶诱导的小鼠白血病L5178Y中甲氨蝶呤多聚谷氨酰化的调节

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Targeted Polymeric Micelles System, Designed to Carry a Combined Cargo of L-Asparaginase and Doxorubicin, Shows Vast Improvement in Cytotoxic Efficacy.靶向聚合物胶束系统旨在携带天冬酰胺酶和阿霉素的联合药物，其细胞毒性功效有显著提高。

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Phase II study of methotrexate, vincristine, pegylated-asparaginase, and dexamethasone (MOpAD) in patients with relapsed/refractory acute lymphoblastic leukemia.甲氨蝶呤、长春新碱、聚乙二醇化天冬酰胺酶和地塞米松（MOpAD）治疗复发/难治性急性淋巴细胞白血病的 II 期研究。

Am J Hematol. 2015 Feb;90(2):120-4. doi: 10.1002/ajh.23886. Epub 2014 Nov 19.

Sequential administration of methotrexate and asparaginase in relapsed or refractory pediatric acute myeloid leukemia.甲氨蝶呤和门冬酰胺酶序贯治疗复发或难治性儿童急性髓系白血病。

Pediatr Blood Cancer. 2013 Jul;60(7):1161-4. doi: 10.1002/pbc.24470. Epub 2013 Jan 17.

Methotrexate and the need for continued research.甲氨蝶呤与持续研究的必要性。

Yale J Biol Med. 1975 May;48(2):97-103.

Refractory acute leukaemia in adults treated with sequential colaspase and high-dose methotrexate.序贯使用天冬酰胺酶和大剂量甲氨蝶呤治疗成人难治性急性白血病。

Br Med J. 1978 Sep 16;2(6140):791-3. doi: 10.1136/bmj.2.6140.791.

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