Ballantyne F C, Fleck A
J Clin Pathol. 1973 Jul;26(7):499-502. doi: 10.1136/jcp.26.7.499.
Evaluation of a commercial preparation of (125)I-labelled albumin for use in the study of albumin metabolism is described. In eight subjects with normal albumin metabolism the proportion of the dose of radioiodide excreted was stable throughout a period of 17 days, indicating that there was no excessive denaturation of the iodinated albumin. Characteristics of albumin metabolism-pool sizes, catabolic rate, etc-were in agreement with currently accepted normal values. It is concluded that this preparation of iodinated albumin is suitable for metabolic use.
本文描述了一种用于白蛋白代谢研究的商业制备的（125）I标记白蛋白的评估。在八名白蛋白代谢正常的受试者中，放射性碘剂量排泄的比例在17天内保持稳定，这表明碘化白蛋白没有过度变性。白蛋白代谢的特征——池大小、分解代谢率等——与目前公认的正常值一致。得出的结论是，这种碘化白蛋白制剂适用于代谢研究。
