成年两栖类心肌细胞体外DNA合成与有丝分裂

DNA synthesis and mitosis in adult amphibian cardiac muscle cells in vitro.

作者信息

Nag A C, Healy C J, Cheng M

出版信息

Science. 1979 Sep 21;205(4412):1281-2. doi: 10.1126/science.472744.

Abstract

High-resolution autoradiography and fine structural analysis of adult newt heart tissue in long-term culture revealed that tritiated thymidine was concentrated in the nuclei of dedifferentiated myocardial cells. Mitotic chromosomes were observed in some of these cells. This demonstrates that adult amphibian myocardial cells in vitro are capable of DNA synthesis and mitosis.

摘要

对长期培养的成年蝾螈心脏组织进行高分辨率放射自显影和精细结构分析发现，氚标记的胸腺嘧啶核苷集中在去分化心肌细胞核中。在其中一些细胞中观察到有丝分裂染色体。这表明成年两栖动物心肌细胞在体外能够进行DNA合成和有丝分裂。