Andersson P, Garry-Andersson A S
Acta Vet Scand. 1973;14(2):225-8. doi: 10.1186/BF03547439.
Amprolium fed to growing chickens in a concentration of 125 p.p.m. in a commercial diet was accompanied by a small but significant decrease in thyroid activity compared with the results for untreated chickens, judged by serum PBI values. The epithelium : colloid relation was lowered. This was presumed to be a consequence of the antagonistic effect of amprolium on thiamine. Payzone feeding, 10 p.p.m. in commercial feed, caused a more pronounced retardation of thyroid activity, judged by the same criteria. A possible connection between the depressed thyroid function and the well-established improvement in weight gain and feed conversion in connection with payzone feeding is discussed.
在商业饲料中以百万分之125的浓度喂给生长中的鸡氨丙啉，与未处理的鸡相比，根据血清蛋白结合碘值判断，甲状腺活性有小幅但显著的下降。上皮细胞与胶体的关系降低。这被认为是氨丙啉对硫胺素拮抗作用的结果。在商业饲料中添加百万分之10的派佐卡因喂养，根据相同标准判断，会导致甲状腺活性更明显的迟缓。文中讨论了甲状腺功能降低与派佐卡因喂养带来的体重增加和饲料转化率改善之间可能存在的联系。
