儿茶酚氧位甲基转移酶的动力学研究。产物抑制作用及儿茶酚结合位点的性质。 - Suppr

Suppr

超能文献

Kinetic studies on catechol O-methyltransferase. Product inhibition and the nature of the catechol binding site.

作者信息

Coward J K, Slixz E P, Wu F Y

出版信息

Biochemistry. 1973 Jun 5;12(12):2291-7. doi: 10.1021/bi00736a017.

DOI:10.1021/bi00736a017

PMID:4736330

Abstract

摘要

相似文献

Kinetic studies on catechol O-methyltransferase. Product inhibition and the nature of the catechol binding site.儿茶酚氧位甲基转移酶的动力学研究。产物抑制作用及儿茶酚结合位点的性质。

Biochemistry. 1973 Jun 5;12(12):2291-7. doi: 10.1021/bi00736a017.

Catechol O-methyltransferase. 2. In vitro inhibition by substituted 8-hydroxyquinolines.

J Med Chem. 1973 Apr;16(4):382-7. doi: 10.1021/jm00262a016.

The purification and kinetic properties of liver microsomal-catechol-o-methyltransferase.

Life Sci. 1974 Mar 16;14(6):1089-1100. doi: 10.1016/0024-3205(74)90233-1.

Kinetic properties of a soluble catechol O-methyltransferase of human liver.

Eur J Biochem. 1972 Apr 24;26(4):560-9. doi: 10.1111/j.1432-1033.1972.tb01799.x.

Catechol O-methyltransferase.

Methods Enzymol. 1981;77:267-72. doi: 10.1016/s0076-6879(81)77036-8.

Catechol O-methyltransferase. 3. Mechanism of pyridoxal 5'-phosphate inhibition.

J Med Chem. 1973 Apr;16(4):387-91. doi: 10.1021/jm00262a017.

Catechol O-methyltransferase. 1. Kinetics of tropolone inhibition.

J Med Chem. 1973 Apr;16(4):377-82. doi: 10.1021/jm00262a015.

A microsomal catechol O-methyltransferase from rat liver.来自大鼠肝脏的微粒体儿茶酚-O-甲基转移酶。

Biochem J. 1972 Nov;130(2):83P-84P. doi: 10.1042/bj1300083p.

Affinity labeling of catechol O-methyltransferase by N-haloacetyl derivatives of 3,5-dimethoxy-4-hydroxyphenylethylamine and 3,4-dimethoxy-5-hydroxyphenylethylamine. Kinetics of inactivation.3,5-二甲氧基-4-羟基苯乙胺和3,4-二甲氧基-5-羟基苯乙胺的N-卤代乙酰基衍生物对儿茶酚-O-甲基转移酶的亲和标记。失活动力学。

Biochemistry. 1975 Oct 7;14(20):4543-51. doi: 10.1021/bi00691a033.

Bisubstrate inhibitors for the enzyme catechol-O-methyltransferase (COMT): influence of inhibitor preorganisation and linker length between the two substrate moieties on binding affinity.儿茶酚-O-甲基转移酶（COMT）的双底物抑制剂：抑制剂预组织以及两个底物部分之间连接子长度对结合亲和力的影响。

Org Biomol Chem. 2003 Jan 7;1(1):42-9. doi: 10.1039/b208690p.

引用本文的文献

Enzymatic Fluoromethylation Enabled by the -Adenosylmethionine Analog -Adenosyl--(fluoromethyl)homotellurocysteine.由S-腺苷甲硫氨酸类似物S-腺苷-S-（氟甲基）高碲半胱氨酸实现的酶促氟甲基化反应

ACS Cent Sci. 2023 May 8;9(5):905-914. doi: 10.1021/acscentsci.2c01385. eCollection 2023 May 24.

Analytical methodologies for sensing catechol--methyltransferase activity and their applications.检测儿茶酚 - 甲基转移酶活性的分析方法及其应用。

J Pharm Anal. 2021 Feb;11(1):15-27. doi: 10.1016/j.jpha.2020.03.012. Epub 2020 Apr 7.

Revealing quantum mechanical effects in enzyme catalysis with large-scale electronic structure simulation.通过大规模电子结构模拟揭示酶催化中的量子力学效应。

React Chem Eng. 2019 Feb 1;4(2):298-315. doi: 10.1039/C8RE00213D. Epub 2018 Nov 29.

Large-scale QM/MM free energy simulations of enzyme catalysis reveal the influence of charge transfer.大规模的量子力学/分子力学自由能模拟酶催化反应揭示了电荷转移的影响。

Phys Chem Chem Phys. 2018 Aug 8;20(31):20650-20660. doi: 10.1039/c8cp03871f.

Structure of aryl -demethylase offers molecular insight into a catalytic tyrosine-dependent mechanism.芳基去甲基酶的结构为酪氨酸依赖性催化机制提供了分子见解。

Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):E3205-E3214. doi: 10.1073/pnas.1619263114. Epub 2017 Apr 3.

Computational Investigation of the Interplay of Substrate Positioning and Reactivity in Catechol O-Methyltransferase.儿茶酚氧位甲基转移酶中底物定位与反应性相互作用的计算研究

PLoS One. 2016 Aug 26;11(8):e0161868. doi: 10.1371/journal.pone.0161868. eCollection 2016.

Deregulation of S-adenosylmethionine biosynthesis and regeneration improves methylation in the E. coli de novo vanillin biosynthesis pathway.S-腺苷甲硫氨酸生物合成与再生的去调控改善了大肠杆菌从头合成香草醛生物合成途径中的甲基化作用。

Microb Cell Fact. 2016 Apr 11;15:61. doi: 10.1186/s12934-016-0459-x.

Oxidative stress in schizophrenia: an integrated approach.精神分裂症中的氧化应激：一种综合方法。

Neurosci Biobehav Rev. 2011 Jan;35(3):878-93. doi: 10.1016/j.neubiorev.2010.10.008. Epub 2010 Oct 23.

N,N-Dimethyltryptamine Production in Phalaris aquatica Seedlings: A Mathematical Model for its Synthesis.水生虉草幼苗中N，N-二甲基色胺的产生：其合成的数学模型

Plant Physiol. 1988 Oct;88(2):315-20. doi: 10.1104/pp.88.2.315.

A semiempirical study on inhibition of catechol O-methyltransferase by substituted catechols.取代儿茶酚对儿茶酚-O-甲基转移酶抑制作用的半经验研究。

J Comput Aided Mol Des. 1998 May;12(3):301-7. doi: 10.1023/a:1007965026738.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验