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[闭塞性动脉硬化的病理生理学现代研究进展]

[Modern aspects of the physiopathology of arteriosclerosis obliterans].

作者信息

Bollinger A

出版信息

Z Gesamte Inn Med. 1979 Apr 15;34(8):87-90.

PMID:473830
Abstract

In a shortened survey new points of view concerning the pathophysiology of disturbances of the peripheral arterial blood supply are discussed. Here the author deals in short with the new hypothesis of the atherogenesis, according to which on the basis of a lesion of the endothelium an aggregation of thrombocytes with following stimulation of the smooth muscle cells of the media develops. The haemodynamic changes by vascular stenoses and obstructions with the possibilities of their recognition are discussed in detail, in which especially examinations under load and phasic measurements of flow are taken into consideration.

摘要

在一份简短的调查报告中,讨论了有关外周动脉血液供应紊乱病理生理学的新观点。在此,作者简要论述了动脉粥样硬化形成的新假说,该假说认为,在内皮损伤的基础上,会发生血小板聚集,继而刺激中膜平滑肌细胞。文中详细讨论了血管狭窄和阻塞引起的血流动力学变化及其识别方法,尤其考虑了负荷试验和血流的阶段性测量。

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