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硫酸氨基葡聚糖(阿特帕龙)对关节病的治疗效果取决于给药方式(关节内或肌肉内)

[The therapeutic effect of glycosaminoglycan polysulfate (Arteparon) in arthroses depending on the mode of administration (intraarticular or intramuscular)].

作者信息

Dettmer N

出版信息

Z Rheumatol. 1979 May-Jun;38(5-6):163-81.

PMID:473929
Abstract

The effect of GAGPS (Arteparon) was investigated on patients with osteoarthritis of hip-joints in dependence from the method of application. By that way 50 patients got each 6 injections with 125 mg/0,5 ml Arteparon intraarticular and 50 patients each 10 injections with 125 mg/0,5 ml Arteparon intramuscular. We have documented the qualities of pain, function and motility of the treated hip-joints. The tests applied have demonstrated that there is no significant difference between the both applications, in both groups the effect was good to the same extent. The therapeutic effect and the further indications by intramuscular administration of the GAGPS are discussed.

摘要

根据应用方法,研究了硫酸软骨素(阿特帕龙)对髋关节骨关节炎患者的疗效。通过这种方式,50名患者每人接受6次125毫克/0.5毫升阿特帕龙关节内注射,50名患者每人接受10次125毫克/0.5毫升阿特帕龙肌肉注射。我们记录了治疗后髋关节的疼痛、功能和活动能力。所应用的测试表明,两种给药方式之间没有显著差异,两组的效果在相同程度上都很好。讨论了肌肉注射硫酸软骨素的治疗效果和进一步的适应症。

相似文献

1
[The therapeutic effect of glycosaminoglycan polysulfate (Arteparon) in arthroses depending on the mode of administration (intraarticular or intramuscular)].硫酸氨基葡聚糖(阿特帕龙)对关节病的治疗效果取决于给药方式(关节内或肌肉内)
Z Rheumatol. 1979 May-Jun;38(5-6):163-81.
2
[Glycosaminoglycanpolysulfate (GAGPS, Arteparon) for basic therapy of arthrosis. III. Biochemical-diagnostic and clinical studies on the intramuscular use of GAGPS].[硫酸氨基葡聚糖多硫酸盐(GAGPS,阿特帕龙)用于骨关节炎的基础治疗。III. 关于肌肉注射GAGPS的生化诊断和临床研究]
Z Rheumatol. 1977 Jul-Aug;36(7-8):269-74.
3
[Comparison of glycosaminoglycan polysulfate (Arteparon) and physiological saline solution in arthrosis of the large joints. Results of a multicenter double-blind study].[大关节骨关节炎中硫酸氨基葡聚糖多硫酸盐(Arteparon)与生理盐水的比较。一项多中心双盲研究的结果]
Z Rheumatol. 1983 Jul-Aug;42(4):223-8.
4
[Chondroprotective and antiarthrotic properties of glycosaminoglycan polysulfate (GAGPS) in gonarthrosis in animal experiments].[硫酸氨基葡聚糖(GAGPS)在动物实验性膝关节炎中的软骨保护和抗关节炎特性]
Z Rheumatol. 1982 Sep-Oct;41(5):219-29.
5
[Experimental confirmation of the antiarthritic activity of glycosaminoglycan polysulfate].[硫酸氨基葡聚糖抗关节炎活性的实验证实]
Z Rheumatol. 1983 Jul-Aug;42(4):178-84.
6
[Clinical studies of intra-articular injections of Arteparon. Retrospective study following the treatment of 754 patients].[关节内注射阿特帕隆的临床研究。对754例患者治疗后的回顾性研究]
Fortschr Med. 1982 Sep 16;100(35):1624-7.
7
[Glycosaminoglycanpolysulfate (GAGPS, Arteparon) for basic therapy of arthrosis. I. Comparative studies, Arteparon forte and physical therapy vs. physical therapy alone].[硫酸氨基葡聚糖多硫酸盐(GAGPS,阿特帕龙)用于骨关节炎的基础治疗。I. 对比研究,强效阿特帕龙与物理治疗联合与单纯物理治疗]
Z Rheumatol. 1977 Jul-Aug;36(7-8):260-4.
8
[In vivo study of the distribution, affinity for cartilage and metabolism of glycosaminoglycan polysulphate (GAGPS, Arteparon)].[硫酸氨基葡聚糖(GAGPS,阿特帕龙)在体内的分布、对软骨的亲和力及代谢的研究]
Z Rheumatol. 1983 Nov-Dec;42(6):355-61.
9
[Comparative studies on the drug therapy of gonarthroses].[膝关节病药物治疗的比较研究]
Fortschr Med. 1975 Jan 23;93(3):133-6.
10
[Conservative treatment of severe osteoarthritis of the knee and hip joints with long-term injections of arteparon].[长期注射阿替帕隆对膝关节和髋关节重度骨关节炎的保守治疗]
Chir Narzadow Ruchu Ortop Pol. 1982;47(1-2):115-8.

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