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硫酸氨基葡聚糖(阿特帕龙)对关节病的治疗效果取决于给药方式(关节内或肌肉内)

[The therapeutic effect of glycosaminoglycan polysulfate (Arteparon) in arthroses depending on the mode of administration (intraarticular or intramuscular)].

作者信息

Dettmer N

出版信息

Z Rheumatol. 1979 May-Jun;38(5-6):163-81.

PMID:473929
Abstract

The effect of GAGPS (Arteparon) was investigated on patients with osteoarthritis of hip-joints in dependence from the method of application. By that way 50 patients got each 6 injections with 125 mg/0,5 ml Arteparon intraarticular and 50 patients each 10 injections with 125 mg/0,5 ml Arteparon intramuscular. We have documented the qualities of pain, function and motility of the treated hip-joints. The tests applied have demonstrated that there is no significant difference between the both applications, in both groups the effect was good to the same extent. The therapeutic effect and the further indications by intramuscular administration of the GAGPS are discussed.

摘要

根据应用方法,研究了硫酸软骨素(阿特帕龙)对髋关节骨关节炎患者的疗效。通过这种方式,50名患者每人接受6次125毫克/0.5毫升阿特帕龙关节内注射,50名患者每人接受10次125毫克/0.5毫升阿特帕龙肌肉注射。我们记录了治疗后髋关节的疼痛、功能和活动能力。所应用的测试表明,两种给药方式之间没有显著差异,两组的效果在相同程度上都很好。讨论了肌肉注射硫酸软骨素的治疗效果和进一步的适应症。

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