Gnezditskiĭ V V, Erokhina L G, Koptelov Iu M, Shchekut'ev G A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1979;79(6):673-9.
Changes in the spectral and integral-temporal characteristics of evoked potentials (EP) to flashes, were studied in 17 epileptic patients and 20 normals. The analysis of EP was done on a background recording and after a 2-minute hyperventilation. It was demonstrated that an epileptization of the brain according to the integral indices of EP is expressed by an increase in the square response, duration of EP (an increase in the duration of the system return to a state of equilibrium), by a higher level of residual noise in a discharge of EP, as well as by an increase in the negative part of EP and a larger instability of responses. The spectral content of EP in epileptic patients demonstrates an increase in amplitude maxima, especially within theta = psi delta ranges. Hyperventilation in epileptic patients evokes a pronounced synchronization of brain bioelectric activity, which leads to a drop of the response intensity and an increase in the level of residual noise in a discharge of EP. The data obtained suggest that the proposed method of EP analysis may be effective in the determination of the intensity in the focus of epileptical activity, as well as in the study of the function of inhibitory mechanisms of convulsive discharges.
对17例癫痫患者和20名正常人进行了研究，观察了闪光诱发电位（EP）的频谱和积分时间特性的变化。在背景记录以及2分钟的过度换气后对EP进行分析。结果表明，根据EP的积分指标，脑癫痫化表现为平方反应增加、EP持续时间延长（系统恢复到平衡状态的持续时间增加）、EP放电中残余噪声水平升高，以及EP负向部分增加和反应的更大不稳定性。癫痫患者EP的频谱内容显示出振幅最大值增加，特别是在θ=ψδ范围内。癫痫患者的过度换气会引起脑生物电活动的明显同步化，这导致反应强度下降和EP放电中残余噪声水平增加。所获得的数据表明，所提出的EP分析方法可能在确定癫痫活动焦点的强度以及研究惊厥放电抑制机制的功能方面有效。
