Hartford M, Ljungman S, Andersson O, Wikstrand J, Berglund G
Acta Med Scand. 1979;205(7):563-8.
Severity of hypertension, frequency of secondary hypertension and prognosis have been compared in two groups of hypertensive men. The first group (n=686) was taken from a blood pressure screening of a total population sample. The other group (n=154) consisted of hypertensive men, referred to a hypertension clinic by physicians. The mean age of the groups was the same, (X=52 years, range 46--59 years). All went through the same investigations and were followed up and treated in a similar way at the hypertension clinic. The referred men had more severe hypertension, as shown by significantly more heart and kidney involvements. They also had a higher incidence of myocardial infarction, implying a poorer prognosis with regard to cardiovascular disease. The analysis shows the importance of a detailed description of studied groups, not only in terms of blood pressure, age and sex, but also with respect to the frequency and degree of present and previous signs of heart and kidney involvement. With such a description it is possible to compare results from different studies regarding pathophysiological mechanisms and the effect of treatment in hypertension.
对两组男性高血压患者的高血压严重程度、继发性高血压发生率及预后进行了比较。第一组（n = 686）来自对总人口样本的血压筛查。另一组（n = 154）由医生转诊至高血压诊所的男性高血压患者组成。两组的平均年龄相同（X = 52岁，范围46 - 59岁）。所有人都接受了相同的检查，并在高血压诊所接受了类似的随访和治疗。转诊患者的高血压更为严重，心脏和肾脏受累明显更多。他们的心肌梗死发生率也更高，这意味着心血管疾病的预后较差。分析表明，详细描述研究组非常重要，不仅要描述血压、年龄和性别，还要描述心脏和肾脏受累的现有及既往体征的频率和程度。有了这样的描述，就可以比较不同研究关于高血压病理生理机制和治疗效果的结果。
