原发性甲状旁腺功能亢进症中的骨质流失。
Bone loss in primary hyperparathyroidism.
作者信息
Gryfe C I
出版信息
Can Med Assoc J. 1973 Sep 15;109(6):479-82.
X-ray images of the second metacarpals of 153 hyperparathyroid subjects were measured and an index of cortical bone was derived. Compared with normal standards, the cortical index was above the 50th percentile in only 17.8% of women and 13.6% of men. Comparing the mean index of hyperparathyroid subjects with the normal indices of each 10-year age group, it was found that the differences were highly significant and were the same for all age groups in each sex. In particular, the difference was not greater between older female hyperparathyroid and normal subjects than it was between younger female hyperparathyroid and normal subjects. It appears that bone involvement in the form of excessive cortical thinning is extremely common in hyperparathyroidism and that sex and age do not further influence its incidence or severity.
对153名甲状旁腺功能亢进患者的第二掌骨进行X线成像测量，并得出皮质骨指数。与正常标准相比，皮质指数仅在17.8%的女性和13.6%的男性中高于第50百分位数。将甲状旁腺功能亢进患者的平均指数与每个10岁年龄组的正常指数进行比较，发现差异具有高度显著性，且在各性别中的所有年龄组均相同。特别是，老年女性甲状旁腺功能亢进患者与正常受试者之间的差异并不比年轻女性甲状旁腺功能亢进患者与正常受试者之间的差异更大。甲状旁腺功能亢进症中以皮质过度变薄形式出现的骨受累似乎极为常见，性别和年龄并不会进一步影响其发病率或严重程度。
Zotero 插件