Van Cauwenberge P B
Allergol Immunopathol (Madr). 1979 Jan-Feb;7(1):13-8.
If medical treatment fails to cure an allergic or vasomotor rhinopathy, we have to look for surgical procedures in trying to relieve the symptoms. Vidian neurectomy is a well known technique, but there still is much discussion about the technique and the long term results. With cryosurgery of the inferior nasal turbinates we obtain a fibrosis and shrinking of these hypertrophied tissues. The nitrous oxide cryosurgery unit we use relies on the Joule-Thomson effect. The specially designed cryoprobe for intranasal procedures is against the medial wall of the turbinate for 2 minutes with freezing to between -50 degrees and -60 degrees C. Thirty-seven patients entered our study. In vasomotor rhinopathy 17 out of 24 patients were completely free of symptoms for at least 3 months, while 4 were better. In allergic rhinopathy, the results are good but we did not reach this high number of completely cured patients. Most of the patients showed a relapse after 3 to 6 months. This is probably due to a regrowth of the autonomic nerve endings. We did not note side efects in the patients included in our study.
如果药物治疗无法治愈过敏性或血管运动性鼻病，我们就必须寻求手术方法来缓解症状。翼管神经切断术是一种众所周知的技术，但关于该技术及其长期效果仍存在诸多争议。通过对下鼻甲进行冷冻手术，我们可使这些肥大组织发生纤维化并萎缩。我们使用的一氧化二氮冷冻手术设备依靠焦耳-汤姆逊效应。专门设计的用于鼻内手术的冷冻探头紧贴鼻甲内侧壁2分钟，冷冻温度在-50摄氏度至-60摄氏度之间。37名患者进入我们的研究。在血管运动性鼻病患者中，24名患者中有17名至少3个月完全无症状，4名症状有所改善。在过敏性鼻病患者中，效果良好，但完全治愈的患者数量未达到那么高。大多数患者在3至6个月后复发。这可能是由于自主神经末梢再生所致。我们在纳入研究的患者中未发现副作用。
