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通过对流免疫电泳检测正常献血者血清中针对某些与III型过敏相关抗原的沉淀抗体。

Precipitating antibodies in sera of normal blood donors against some antigens related to type III allergy, detected by counterimmunoelectrophoresis.

作者信息

Meyer J C, Trachsel H

出版信息

Allergol Immunopathol (Madr). 1979 May-Jun;7(3):205-10.

PMID:474328
Abstract

Precipitating antibodies against five antigens, staphylococcus aureus, candida albicans, cotton wool dust, house dust and tetanus toxoid, related to type III allergy (Arthus reaction) were estimated in 100 sera of normal blood donors by the counterimmunoelectrophoresis technique. The three antigens staphylococcus aureus, candida and cotton wool dust exhibited rather high titres of precipitins in sera of normal blood donors, whereas nearly 80% of the sera yielded no precipitins against house dust and tetanus toxoid. For diagnostic purposes the borderline titres were estimated as follows: 1:8 for staphylococcus aureus, 1:16 for candida albicans and 1:8 for cotton wool dust. Even low titres with the house dust antigen indicated a pathogenic situation.

摘要

采用对流免疫电泳技术,对100名正常献血者的血清中针对5种抗原(金黄色葡萄球菌、白色念珠菌、棉尘、屋尘和破伤风类毒素)的沉淀抗体进行了检测,这些抗原与III型过敏反应(阿瑟氏反应)相关。在正常献血者的血清中,金黄色葡萄球菌、白色念珠菌和棉尘这三种抗原呈现出相当高滴度的沉淀素,而近80%的血清对屋尘和破伤风类毒素未产生沉淀素。为了诊断目的,临界滴度估计如下:金黄色葡萄球菌为1:8,白色念珠菌为1:16,棉尘为1:8。即使是屋尘抗原的低滴度也表明存在致病情况。

相似文献

1
Precipitating antibodies in sera of normal blood donors against some antigens related to type III allergy, detected by counterimmunoelectrophoresis.通过对流免疫电泳检测正常献血者血清中针对某些与III型过敏相关抗原的沉淀抗体。
Allergol Immunopathol (Madr). 1979 May-Jun;7(3):205-10.
2
Incidence of serum precipitins against organic-dust antigens in different populations by counterimmunoelectrophoresis.通过对流免疫电泳检测不同人群中针对有机粉尘抗原的血清沉淀素发生率。
Chest. 1975 Dec;68(6):753-8. doi: 10.1378/chest.68.6.753.
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[On byssinosis (cotton dust lung)--is it an Arthus reaction? Detection of precipitating antibodies against cotton dust extracts].[关于棉尘肺(棉屑沉着病)——它是一种阿瑟氏反应吗?棉尘提取物沉淀抗体的检测]
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Precipitating antibodies against organic dust antigens in human sera by counterimmunoelectrophoresis.
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[Comparison of immunodiffusion and counterimmunoelectrophoresis for the detection of precipitating antibodies against Candida and Aspergillus antigens].免疫扩散法与对流免疫电泳法检测抗念珠菌和曲霉菌抗原沉淀抗体的比较
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Precipitating antibodies against Staphylococcus aureus in serum from patients with staphylococcal septicaemia, investigated by means of quantitative immunoelectrophoretic methods.采用定量免疫电泳法对金黄色葡萄球菌败血症患者血清中抗金黄色葡萄球菌的沉淀抗体进行研究。
Acta Pathol Microbiol Scand B. 1981 Aug;89(4):261-6. doi: 10.1111/j.1699-0463.1981.tb00186_89b.x.

引用本文的文献

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Skin test and lymphocyte stimulation in delayed hypersensitivity against Staphylococcus aureus antigens. Development of hypersensitivity.针对金黄色葡萄球菌抗原的迟发型超敏反应中的皮肤试验和淋巴细胞刺激。超敏反应的发展。
Arch Dermatol Res. 1980;267(3):291-9. doi: 10.1007/BF00403850.