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睾丸恶性肿瘤患者单侧睾丸切除术后及放疗后的生育能力

Fertility after unilateral orchidectomy and radiotherapy for patients with malignant tumours of the testis.

作者信息

Smithers D W, Wallace D M, Austin D E

出版信息

Br Med J. 1973 Oct 13;4(5884):77-9. doi: 10.1136/bmj.4.5884.77.

Abstract

The results of treatment for patients with seminoma of the testis by orchidectomy and irradiation are so satisfactory that retroperitoneal lymph node dissection is no longer practised. However, this operation is still used routinely in some centres for patients with testicular teratomas despite the lack of evidence that it gives better results than those obtained with irradiation followed by removal of lymphographically demonstrable residual tumour and in the face of the high incidence of ejaculatory impotence which follows. On grounds of preservation of sexual function and fertility there is a great advantage to be gained from the latter form of treatment. Thirty-four of our patients between the ages of 25 and 45 years treated by irradiation to the para-aortic and iliac nodes for testicular tumours fathered 52 children to term after their treatment.

摘要

睾丸精原细胞瘤患者经睾丸切除术和放射治疗后的效果非常令人满意,以至于不再进行腹膜后淋巴结清扫术。然而,尽管缺乏证据表明该手术比放射治疗后切除淋巴造影显示的残留肿瘤能取得更好的效果,且存在射精功能障碍发生率高的问题,但在一些中心,对于睾丸畸胎瘤患者仍常规进行该手术。基于性功能和生育能力的保留,后一种治疗方式具有很大优势。我们对年龄在25至45岁之间的34例睾丸肿瘤患者进行了腹主动脉旁和髂淋巴结放射治疗,这些患者在治疗后足月产下了52名子女。

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引用本文的文献

1
Radiotherapy of testicular tumours.睾丸肿瘤的放射治疗
Proc R Soc Med. 1974 Apr;67(4):300-3. doi: 10.1177/003591577406700443.

本文引用的文献

1
Radiotherapy in the treatment of patients with seminomas and teratomas of the testicle.
Br J Urol. 1962 Dec;34:422-35. doi: 10.1111/j.1464-410x.1962.tb06525.x.
6
Radiotherapy for patients with tumours of the testicle.
Br J Urol. 1971 Feb;43(1):83-92. doi: 10.1111/j.1464-410x.1971.tb04938.x.
7
Fertility in patients treated for malignant testicular tumors.
J Urol. 1973 Feb;109(2):293-5. doi: 10.1016/s0022-5347(17)60407-5.

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