自身免疫性溶血性贫血七年后终发展为霍奇金淋巴瘤。
Autoimmune hemolytic anemia terminating seven years later in Hodgkin's disease.
作者信息
Cazenave J P, Gagnon J A, Girouard E, Bastarache A
出版信息
Can Med Assoc J. 1973 Oct 20;109(8):748-9 passim.
Abstract
A 64-year-old woman was treated during 7(1/2) years for an isolated AIHA by transfusions, prednisone and splenectomy. The autoantibody was a warm-type IgG with anti-e specificity. At autopsy, generalized Hodgkin's disease of mixed cellularity was found. Only 11 similar cases of hemolytic anemia preceding the development of Hodgkin's disease have been reported in the literature. This association suggests a possible underlying defect in the immune system of the host.
摘要
一名64岁女性因单纯自身免疫性溶血性贫血（AIHA）接受了7年半的输血、泼尼松和脾切除术治疗。自身抗体为具有抗 - e特异性的温型IgG。尸检发现为混合细胞型的全身性霍奇金病。文献中仅报道了11例在霍奇金病发生之前出现溶血性贫血的类似病例。这种关联提示宿主免疫系统可能存在潜在缺陷。
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