三磷酸腺苷对组织匀浆中蛋白水解的明显刺激作用。
The apparent stimulation of proteolysis by adenosine triphosphate in tissue homogenates.
作者信息
Goldspink D F, Goldberg A L
出版信息
Biochem J. 1973 Jul;134(3):829-32. doi: 10.1042/bj1340829.
Abstract
Reports that ATP promotes proteolysis in tissue homogenates were reinvestigated. Although ATP increased production of material reacting with ninhydrin or Folin-phenol reagent, ATP did not stimulate protein degradation in such extracts. AMP and adenosine acted similarly to ATP. Deamination of the added nucleotides to produce ammonia caused the increase in ninhydrin-positive material.
摘要
关于ATP促进组织匀浆中蛋白质水解的报道被重新研究。尽管ATP增加了与茚三酮或福林 - 酚试剂反应的物质的产生，但ATP并未刺激此类提取物中的蛋白质降解。AMP和腺苷的作用与ATP相似。添加的核苷酸脱氨产生氨导致茚三酮阳性物质增加。
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本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
MEASUREMENT OF LOW ENERGY BETA-EMITTERS IN AQUEOUS SOLUTION BY LIQUID SCINTILLATION COUNTING OF EMULSIONS.通过乳液的液体闪烁计数法测量水溶液中的低能β发射体。
Anal Chem. 1965 Jun;37:854-7. doi: 10.1021/ac60226a017.
3
QUANTITATIVE RANGE OF NESSLER'S REACTION WITH AMMONIA.
Clin Chem. 1963 Aug;12:417-22.
4
A fluorometric method for the estimation of tyrosine in plasma and tissues.一种用于估算血浆和组织中酪氨酸的荧光测定法。
J Lab Clin Med. 1957 Nov;50(5):733-6.
5
Chemistry and biochemistry of xanthine oxidase.黄嘌呤氧化酶的化学与生物化学
Adv Enzymol Relat Subj Biochem. 1956;17:293-328. doi: 10.1002/9780470122624.ch7.
6
Reassessment of alkaline proteases and the presence of xanthine oxidase in mouse muscle.对小鼠肌肉中碱性蛋白酶及黄嘌呤氧化酶存在情况的重新评估。
Arch Biochem Biophys. 1969 Sep;133(2):359-65. doi: 10.1016/0003-9861(69)90464-0.
7
8
Protein catabolism in rat liver homogenates. A re-evaluation of the energy requirement for protein catabolism.
J Biol Chem. 1970 Aug 25;245(16):4001-8.
9
The rapid separation of nucleotides in cell extracts using high-pressure liquid chromatography.利用高压液相色谱法快速分离细胞提取物中的核苷酸。
J Chromatogr. 1970 Oct 21;52(2):257-72. doi: 10.1016/s0021-9673(01)96573-2.
10
ATP activation of the neutral proteolytic activity. A widespread phenomenon.三磷酸腺苷（ATP）对中性蛋白水解活性的激活。一种普遍现象。
Proc Soc Exp Biol Med. 1971 Oct;138(1):28-30. doi: 10.3181/00379727-138-35825.
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