Zwart H H, Hicks G, Schuster B, Nathan M, Tabrah F, Wenzke F, Ahmed T, DeWall R A
Ann Thorac Surg. 1979 Aug;28(2):158-65. doi: 10.1016/s0003-4975(10)63774-5.
The Lillehei-Kaster valve was used in 215 patients over a 7-year period. The aortic valve was replaced in 81 of them. Hospital mortality was 21% (17 patients). Ten patients were lost to follow-up and long-term mortality was 5% (3 patients). The incidence of thromboembolism was 2.6 per 100 patient-years, and actuarial survival was 96% at 5 and 87% at 7 years. Mitral valve replacement was performed in 108 patients. Hospital mortality was 20% (22 patients), 24 patients were lost to follow-up, and long-term mortality was 13% (11 patients). The combined incidence of thromboembolism was 5.0 per 100 patient-years, and actuarial survival was 81% at 5 years and 75% at 7 years. In both groups, the majority of patients improved clinically. Fifteen patients had double-valve replacement, and 11 had coronary revascularization in addition to valve replacement.
在7年期间，215例患者使用了 Lillehei-Kaster 瓣膜。其中81例患者进行了主动脉瓣置换。医院死亡率为21%（17例患者）。10例患者失访，长期死亡率为5%（3例患者）。血栓栓塞发生率为每100患者年2.6例，5年时精算生存率为96%，7年时为87%。108例患者进行了二尖瓣置换。医院死亡率为20%（22例患者），24例患者失访，长期死亡率为13%（11例患者）。血栓栓塞的综合发生率为每100患者年5.0例，5年时精算生存率为81%，7年时为75%。两组中，大多数患者临床症状改善。15例患者进行了双瓣膜置换，11例患者除瓣膜置换外还进行了冠状动脉血运重建。
