Swanson M R, Biggers J A, Remmers A R, Sarles H E, Nelson R M, Fish J C
Arch Intern Med. 1979 Sep;139(9):989-91.
Autonomous hyperparathyroidism occurred in 15% of 152 patients maintained by long-term home dialysis during the past nine years. Twenty-two patients with elevated serum parathormone levels and progressive bone disease in the presence of normal serum phosphate and calcium levels were treated by subtotal parathyroidectomy. All had parathyroid hyperplasia. Eighteen of the 22 patients are presently alive and undergo dialysis. Symptoms of bone pain, pruritus, and muscle cramps had improved in three fourths of the patients. The serum parathormone level decreased from a preoperative average of 576 muLEq/mL to an average of 188 muLEq/mL postoperatively. All 18 patients, observed for six to 77 months, showed improvement in x-ray films of their bone disease. The autonomous hyperparathyroidism of end-stage renal disease is corrected by subtotal parathyroidectomy, and the effect is sustained.
在过去九年中，152例长期接受家庭透析的患者中有15%发生了自主性甲状旁腺功能亢进。22例血清甲状旁腺激素水平升高且在血清磷酸盐和钙水平正常的情况下患有进行性骨病的患者接受了甲状旁腺次全切除术治疗。所有患者均有甲状旁腺增生。22例患者中有18例目前仍存活并接受透析。四分之三的患者骨痛、瘙痒和肌肉痉挛症状有所改善。血清甲状旁腺激素水平从术前平均576 μEq/mL降至术后平均188 μEq/mL。观察的所有18例患者，时间为6至77个月，其骨病的X线片显示有所改善。终末期肾病的自主性甲状旁腺功能亢进通过甲状旁腺次全切除术得以纠正，且效果持久。
