无蛋白饮食对实验动物淀粉样蛋白合成的抑制作用。初步报告。
Inhibition of amyloid synthesis in experimental animals by a protein free diet. A preliminary report.
作者信息
Kedar I, Ravid M, Sohar E
出版信息
Br J Exp Pathol. 1973 Oct;54(5):553-4.
Abstract
Amyloidosis was induced by casein injections in mice allocated to glucose, purina and casein dietary regimens. Amyloid was not found in the glucose fed mice. By contrast, amyloid was present in the spleen of purina fed animals and in the spleen, liver and kidney of those fed casein. It seems therefore that adequate protein intake is essential for the consummation of an amyloidogenic stimulus.
摘要
通过给分配到葡萄糖、普瑞纳和酪蛋白饮食方案的小鼠注射酪蛋白来诱发淀粉样变性。喂食葡萄糖的小鼠未发现淀粉样物质。相比之下，喂食普瑞纳的动物脾脏中存在淀粉样物质，而喂食酪蛋白的动物脾脏、肝脏和肾脏中存在淀粉样物质。因此，充足的蛋白质摄入对于引发淀粉样变性刺激似乎至关重要。
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