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兔脂质代谢的神经源性调节。针刺降胆固醇作用的一种机制。

Neurogenic regulation of lipid metabolism in the rabbit. A mechanism for the cholesterol-lowering effect of acupuncture.

作者信息

Wu C C, Hsu C J

出版信息

Atherosclerosis. 1979 Jun;33(2):153-64. doi: 10.1016/0021-9150(79)90112-6.

DOI:10.1016/0021-9150(79)90112-6
PMID:475876
Abstract

Plasma and aortic cholesterol levels are known to fall significantly after needling at the specific point which is innervated by a branch of the deep peroneal nerve. Different types of stimulation were applied to the specific nerve, using solely needling, injection of normal saline with needling and injection of a small dose of novocain with needling at the specific point in several groups of rabbits fed a high cholesterol diet for two or three weeks. Significant decreases in plasma and aortic cholesterol were obtained in the combined acupuncture group after one or two weeks of acupuncture. When the specific point was blocked by injection of a larger dose of novocain or the deep peroneal nerve was cut, then needling at the specific point lost its hypocholesterolemic effect. It is thus suspected that stimulation of sensory receptors of the deep peroneal nerve at the specific point may be the mechanism of the cholesterol-lowering action of acupuncture.

摘要

已知在由腓深神经分支支配的特定穴位针刺后,血浆和主动脉胆固醇水平会显著下降。在几组喂食高胆固醇饮食两到三周的兔子中,于特定穴位仅采用针刺、针刺配合注射生理盐水以及针刺配合注射小剂量奴夫卡因等不同方式对特定神经进行刺激。针刺一到两周后,联合针刺组的血浆和主动脉胆固醇显著降低。当通过注射较大剂量奴夫卡因阻断特定穴位或切断腓深神经时,在该特定穴位针刺便失去其降胆固醇作用。因此推测,在特定穴位刺激腓深神经的感觉感受器可能是针刺降胆固醇作用的机制。

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