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正常猪和全胃切除猪血液及肝脏中的维生素B12

Vitamin B12 in the blood and in the liver of normal and of totally gastrectomized pigs.

作者信息

Petri S, Petri C, Rasmussen F

出版信息

Acta Vet Scand. 1973;14(3):421-7. doi: 10.1186/BF03547429.

DOI:10.1186/BF03547429
PMID:4758784
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8559826/
Abstract

The concentration of vitamin R in the blood was studied in five totally gastrectomized pigs followed for 10–18 months, and in four controls followed for 5¼–8 months. The concentration of vitamin B12 in the liver was investigated in three pigs of each group. The content of vitamin B in the blood was of the same magnitude in both groups. Thus, removal of the stomach does not compromise the normal presence of this vitamin in the blood. The B content in the liver was also unaffected by the operation, whereas it was increased after simultaneous administration of vitamin B.

摘要

对5只全胃切除的猪进行了10 - 18个月的跟踪研究,测定其血液中维生素R的浓度,并对4只对照猪进行了5¼ - 8个月的跟踪研究。对每组中的3头猪的肝脏中维生素B12的浓度进行了研究。两组血液中维生素B的含量处于相同水平。因此,切除胃不会影响这种维生素在血液中的正常存在。肝脏中的B含量也不受手术影响,而在同时给予维生素B后会增加。

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引用本文的文献

1
Anemia and growth retardation in totally gastrectomized swine.全胃切除猪的贫血与生长发育迟缓
Acta Vet Scand. 1980;21(2):197-208. doi: 10.1186/BF03546883.

本文引用的文献

1
Effects of Gastro-Intestinal Resections in Swine on the Anti-Anemia Potency of the Liver: With Observations on the Nature and Sources of the Materials Effective in Pernicious Anemia.猪胃肠道切除对肝脏抗贫血效能的影响:关于恶性贫血有效物质的性质和来源的观察
Yale J Biol Med. 1940 Dec;13(2):259-78.
2
On the curative effect of pure duodenal secretion from swine in cases of pernicious anemia.猪纯十二指肠分泌物对恶性贫血病例的疗效研究
Acta Med Scand. 1948;131(Suppl 206):311-3. doi: 10.1111/j.0954-6820.1948.tb12053.x.
3
Observations on the histo-topographic localization of the vitamin B12 binding factor in the fundus, pylorus and duodenum.
关于维生素B12结合因子在胃底、幽门和十二指肠的组织-地形定位的观察。
Acta Pathol Microbiol Scand Suppl (1926). 1955;105:104-17.
4
Dissertations in honor of Svend Petri, presented by his friends and pupils on his 60th birthday, August 18, 1895 to August 18, 1955.纪念斯文德·彼得里的论文集,由他的朋友和学生在他60岁生日之际呈上,时间跨度为1895年8月18日至1955年8月18日。
Acta Pathol Microbiol Scand Suppl (1926). 1955;105:3-242.
5
GASTRIC INTRINSIC FACTOR AND ITS FUNCTION IN THE METABOLISM OF VITAMIN B12.胃内因子及其在维生素B12代谢中的作用。
Physiol Rev. 1963 Oct;43:529-849. doi: 10.1152/physrev.1963.43.4.529.
6
Microbiological assay of vitamin B12.维生素B12的微生物测定法。
Methods Biochem Anal. 1954;1:81-113. doi: 10.1002/9780470110171.ch4.
7
[Paracrine cells in the gastrointestinal canal. Site of storage of biogenic amines, gastrointestinal polypeptide hormones and absorption factors].
Nord Med. 1971 Feb 11;85(6):169-74.
8
Effect of vitamin B6 upon gastroprival central nervous system degenerations. 3.
Acta Med Scand. 1970 Jan-Feb;187(1-2):129-31. doi: 10.1111/j.0954-6820.1970.tb02919.x.
9
[Anesthesia in pigs using phencyclidine and halothane].
Nord Vet Med. 1971 Jun;23(6):281-7.