用5,6 - 二羟基色胺（一种长效的脑血清素选择性耗竭剂）脑室内预处理的大鼠中，吗啡的抗伤害感受活性降低。 - Suppr

Suppr

超能文献

Decreased antinociceptive activity of morphine in rats pretreated intraventricularly with 5,6-dihydroxytryptamine, a long-lasting selective depletor of brain serotonin.

作者信息

Genovese E, Zonta N, Mantegazza P

出版信息

Psychopharmacologia. 1973 Oct 15;32(4):359-64. doi: 10.1007/BF00429472.

DOI:10.1007/BF00429472

PMID:4760858

Abstract

摘要

相似文献

Decreased antinociceptive activity of morphine in rats pretreated intraventricularly with 5,6-dihydroxytryptamine, a long-lasting selective depletor of brain serotonin.用5,6 - 二羟基色胺（一种长效的脑血清素选择性耗竭剂）脑室内预处理的大鼠中，吗啡的抗伤害感受活性降低。

Psychopharmacologia. 1973 Oct 15;32(4):359-64. doi: 10.1007/BF00429472.

Effects of 5,6-dihydroxytryptamine on monoaminergic neurones in the central nervous system of the rat.5,6-二羟基色胺对大鼠中枢神经系统中单胺能神经元的影响。

J Neurochem. 1972 Jun;19(6):1587-97. doi: 10.1111/j.1471-4159.1972.tb05102.x.

Neurotoxicity of hydroxylated tryptamines: structure-activity relationships. 1. Long-term effects on monoamine content and fluorescence morphology of central monoamine neurons.羟基色胺的神经毒性：构效关系。1. 对中枢单胺能神经元单胺含量和荧光形态的长期影响。

Acta Physiol Scand Suppl. 1975;429:5-27.

Tryptophan hydroxylase of the central nervous system: effect of intraventricular 5,6- and 5,7-dihydroxytryptamine.中枢神经系统的色氨酸羟化酶：脑室内注射5,6-和5,7-二羟基色胺的影响

Adv Biochem Psychopharmacol. 1974;10:93-101.

Effects of 5,6-dihydroxytryptamine on nerve terminal serotonin and serotonin uptake in the rat brain.5,6-二羟基色胺对大鼠脑内神经末梢5-羟色胺及5-羟色胺摄取的影响

Brain Res. 1973 Apr 13;53(1):117-27. doi: 10.1016/0006-8993(73)90771-3.

Long-lasting selective depletion of brain serotonin by 5,6-dihydroxytryptamine.5,6-二羟基色胺对脑血清素的长期选择性耗竭。

Acta Physiol Scand Suppl. 1971;373:1-15.

Influence of 5,6-dihydroxytryptamine on morphine tolerance and physical dependence.5,6-二羟基色胺对吗啡耐受性和身体依赖性的影响。

Eur J Pharmacol. 1973 Mar;21(3):331-6. doi: 10.1016/0014-2999(73)90135-0.

Opposed behavioral syndromes in rats with partial and more complete central serotonergic lesions made with 5,6 dihydroxytryptamine.用5,6-二羟基色胺造成部分及更完全的中枢5-羟色胺能损伤的大鼠中相反的行为综合征

Psychopharmacologia. 1974 Jun 18;37(1):67-79. doi: 10.1007/BF00426684.

Chemically induced degeneration of indoleamine-containing nerve terminals in rat brain.化学诱导大鼠脑内含吲哚胺神经末梢的变性

Brain Res. 1972 Mar 10;38(1):228-32. doi: 10.1016/0006-8993(72)90610-5.

Chemical lesioning of central monoamine axons by means of 5,6-dihydroxytryptamine and 5,7-dihydroxytryptamine.利用5,6-二羟基色胺和5,7-二羟基色胺对中枢单胺能轴突进行化学损伤。

Adv Biochem Psychopharmacol. 1974;10:13-33.

引用本文的文献

Evidence that 5-hydroxytryptamine in the forebrain is involved in naloxone-precipitated jumping in morphine-dependent rats.有证据表明，前脑内的5-羟色胺参与了吗啡依赖大鼠中纳洛酮诱发的跳跃反应。

Br J Pharmacol. 1983 Aug;79(4):993-6. doi: 10.1111/j.1476-5381.1983.tb10546.x.

Test-specific effects of the 5-HT reuptake inhibitors alaproclate and zimelidine on pain sensitivity and morphine analgesia.5-羟色胺再摄取抑制剂阿普氯胺和齐美利定对疼痛敏感性及吗啡镇痛作用的试验特异性效应。

J Neural Transm. 1980;47(4):253-71. doi: 10.1007/BF01247321.

The effects of acutely administered analgesics on the turnover of noradrenaline and dopamine in various regions of the rat brain.急性给予镇痛药对大鼠脑不同区域去甲肾上腺素和多巴胺周转的影响。

Br J Pharmacol. 1974 Oct;52(2):159-65. doi: 10.1111/j.1476-5381.1974.tb09696.x.

Studies on the separate roles of forebrain and spinal serotonin in morphine analgesia.

Naunyn Schmiedebergs Arch Pharmacol. 1986 Mar;332(3):208-12. doi: 10.1007/BF00504855.

Role of ascending and descending serotonergic pathways in the antinociceptive effect of baclofen.5-羟色胺能上行和下行通路在巴氯芬镇痛作用中的作用。

Naunyn Schmiedebergs Arch Pharmacol. 1988 Apr;337(4):359-65. doi: 10.1007/BF00169524.

Psychopharmacological studies on (--)-nuciferine and its Hofmann degradation product atherosperminine.(-)-荷叶碱及其霍夫曼降解产物乌药碱的精神药理学研究。

Psychopharmacology (Berl). 1978 Sep 15;59(1):29-33. doi: 10.1007/BF00428026.

Effects of narcotic analgesics on the uptake and release of 5-hydroxytryptamine in rat synaptosomal preparations.麻醉性镇痛药对大鼠突触体制剂中5-羟色胺摄取和释放的影响。

Br J Pharmacol. 1978 Sep;64(1):75-82. doi: 10.1111/j.1476-5381.1978.tb08643.x.

Central sites and mechanisms of the hypotensive and bradycardic effects of the narcotic analgesic agent fentanyl.麻醉性镇痛药芬太尼降压和减慢心率作用的中枢部位及机制。

Naunyn Schmiedebergs Arch Pharmacol. 1977 Feb;296(3):255-61. doi: 10.1007/BF00498691.

Analgesia produced by morphine when acting from the liquor space.吗啡从脑脊液间隙起作用时产生的镇痛作用。

Br J Pharmacol. 1976 Nov;58(3):383-93. doi: 10.1111/j.1476-5381.1976.tb07715.x.

本文引用的文献

A SENSITIVE METHOD FOR SPECTROPHOTOFLUOROMETRIC ASSAY OF CATECHOLAMINES.一种用于儿茶酚胺分光光度荧光测定的灵敏方法。

Int J Neuropharmacol. 1964 Dec;3:643-9. doi: 10.1016/0028-3908(64)90089-9.

ANTAGONISM OF THE ANALGETIC EFFECT OF MORPHINE IN MICE BY TETRABENAZINE AND RESERPINE.丁苯那嗪和利血平对小鼠吗啡镇痛作用的拮抗作用

Arch Int Pharmacodyn Ther. 1964 Jun 1;149:484-92.

Synergism of amines and antagonism of reserpine to morphine analgesia.胺类的协同作用及利血平对吗啡镇痛的拮抗作用。

Proc Soc Exp Biol Med. 1958 Jan;97(1):97-100. doi: 10.3181/00379727-97-23656.

Reserpine antagonism of morphine analgesia in mice.利血平对小鼠吗啡镇痛作用的拮抗作用。

Proc Soc Exp Biol Med. 1954 Dec;87(3):614-5. doi: 10.3181/00379727-87-21461.

Effect of reserpine and alpha-methyl-tyrosine on morphine analgesia.利血平和α-甲基酪氨酸对吗啡镇痛作用的影响。

Int J Neuropharmacol. 1968 May;7(3):283-92. doi: 10.1016/0028-3908(68)90035-x.

A method for the determination of serotonin and norepinephrine in discrete areas of rat brain.一种测定大鼠脑离散区域中血清素和去甲肾上腺素的方法。

Int J Neuropharmacol. 1968 May;7(3):275-81. doi: 10.1016/0028-3908(68)90034-8.

Antagonism of the analgesic effect of morphine and other drugs by p-chlorophenylalanine, a serotonin depletor.对氯苯丙氨酸（一种血清素耗竭剂）对吗啡及其他药物镇痛作用的拮抗作用。

Psychopharmacologia. 1968;12(4):278-85. doi: 10.1007/BF00401407.

The effects of p-chlorophenylalanine, a serotonin depletor, on avoidance acquisition, pain sensitivity and related behavior in the rat.对氯苯丙氨酸（一种血清素消耗剂）对大鼠回避学习、痛觉敏感性及相关行为的影响。

Psychopharmacologia. 1967;10(3):204-19. doi: 10.1007/BF00401382.

Rapid method for the determination of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in small regions of rat brain.大鼠脑小区域中5-羟色胺和5-羟吲哚乙酸的快速测定方法。

Br J Pharmacol. 1970 Jul;39(3):653-5. doi: 10.1111/j.1476-5381.1970.tb10373.x.

Reduced effect of morphine in midbrain raphe lesioned rats.中脑缝际核损伤大鼠中吗啡作用减弱。

Eur J Pharmacol. 1970;10(3):339-43. doi: 10.1016/0014-2999(70)90205-0.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验