兔回肠对中性氨基酸摄取的钠依赖性

Sodium dependence of neutral amino acid uptake into rabbit ileum.

作者信息

Smith M W, Sepulveda F V

出版信息

Biochim Biophys Acta. 1979 Aug 7;555(2):374-8. doi: 10.1016/0005-2736(79)90179-2.

Abstract

Alanine uses two mediated pathways to enter the rabbit ileal mucosa. Present results suggest that one of them (Km = 4.1 mM) is fully dependent on sodium in the mucosal medium, while the other (Km = 91 mM) is sodium-independent. Similar results are obtained for methionine and serine. Reinterpretation of previous alanine/sodium coupling coefficients suggests that two sodium ions per alanine molecule are transported via the high affinity system.

摘要

丙氨酸通过两条介导途径进入兔回肠黏膜。目前的结果表明，其中一条途径（Km = 4.1 mM）完全依赖于黏膜介质中的钠，而另一条途径（Km = 91 mM）则不依赖于钠。蛋氨酸和丝氨酸也得到了类似的结果。对先前丙氨酸/钠偶联系数的重新解释表明，每个丙氨酸分子通过高亲和力系统转运两个钠离子。