Goren M B, Toubiana R
Biochim Biophys Acta. 1979 Jul 27;574(1):64-9. doi: 10.1016/0005-2760(79)90085-7.
Small quantities of cord factor (trehalose-6,6'-dimycolates) can be readily and almost quantitatively permethylated in anhydrous diethyl ether/dimethylformamide mixtures with CH3I and NaH-oil dispersion in the presence of molecular sieve. Hydrolysis of the permethylated products from cord factor "Peurois" and 'P3-Aoyama-b' prove these to be 6,6'-dimycolates. Experiments with a 4-palmitoyl glucose suggest that acyl migration in this system may not occur.
在分子筛存在下，少量的索状因子（海藻糖 - 6,6'-二霉菌酸酯）可在无水乙醚/二甲基甲酰胺混合物中，与碘甲烷和氢化钠 - 油分散体轻松且几乎定量地进行全甲基化反应。对来自索状因子“Peurois”和“P3 - Aoyama - b”的全甲基化产物进行水解，证明它们是6,6'-二霉菌酸酯。用4 - 棕榈酰葡萄糖进行的实验表明，该体系中可能不会发生酰基迁移。
