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血红蛋白A2和血红蛋白F实验室间定量分析报告。

A report on the interlaboratory quantitation of haemoglobin A2 and haemoglobin F.

作者信息

White J M, Lewis S M

出版信息

J Clin Pathol. 1973 Nov;26(11):864-7. doi: 10.1136/jcp.26.11.864.

Abstract

An interlaboratory trial of the quantitation of Hb A(2) and Hb F has been carried out on two samples of blood by 90 laboratories in the British Isles. The results have been compared with those obtained by four reference laboratories. Overall, the correlation was very poor and indicated that the methods used have to be standardized before interlaboratory values become meaningful. Moreover, in many laboratories the level of Hb A(2) in a patient with proven beta thalassaemia was not reported as being increased.

摘要

不列颠群岛的90个实验室对两份血样进行了血红蛋白A₂(Hb A₂)和血红蛋白F(Hb F)定量的实验室间试验。将结果与四个参考实验室获得的结果进行了比较。总体而言,相关性非常差,这表明在实验室间数值变得有意义之前,所使用的方法必须标准化。此外,在许多实验室中,已确诊的β地中海贫血患者的Hb A₂水平并未报告为升高。

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