Rissanen V
Cardiology. 1979;64(5):289-302. doi: 10.1159/000170626.
Clinicopathologic and epidemiological aspects of coronary artery disease (CAD) in relation to sudden death (SD) were studied in three postmortem series, two of sudden cardiac death and one of male violent death. There appears to be a critical level of severity of CAD which determines the risk of SD. The more severe the CAD within this range, the higher is the risk. Every annual cohort of SDs includes many patients with extremely severe, or 'burned-out', disease. CAD alone, however, is not a selective factor for sudden or not-sudden death. Epidemiological analysis (a) determines the age and frequency of persons reaching the critical risk level of CAD severity in the population (atherogenic factors); (b) influences the selection of the SD victims from the critical population (precipitating factors), and (c) determines the individual variation of CAD severity with which coronary heart disease and SD manifest themselves (sensitising and protecting factors).
在三个尸检系列中研究了与猝死（SD）相关的冠状动脉疾病（CAD）的临床病理和流行病学方面，其中两个是心源性猝死系列，一个是男性暴力死亡系列。似乎存在一个CAD严重程度的临界水平，它决定了SD的风险。在此范围内CAD越严重，风险越高。每年的SD队列中都包括许多患有极其严重或“终末期”疾病的患者。然而，仅CAD并不是猝死或非猝死的选择性因素。流行病学分析（a）确定人群中达到CAD严重程度临界风险水平的人的年龄和频率（致动脉粥样硬化因素）；（b）影响从临界人群中选择SD受害者（诱发因素），以及（c）确定CAD严重程度的个体差异，冠心病和SD据此表现出来（致敏和保护因素）。
