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Pharmacokinetics and pharmacodynamics as well as metabolism following orally and intravenously administered C14-glipizide, a new antidiabetic.

作者信息

Schmidt H A, Schoog M, Schweer K H, Winkler E

出版信息

Diabetologia. 1973 Sep:320-30. doi: 10.1007/BF01218442.

DOI:10.1007/BF01218442
PMID:4772978
Abstract
摘要

相似文献

1
Pharmacokinetics and pharmacodynamics as well as metabolism following orally and intravenously administered C14-glipizide, a new antidiabetic.
Diabetologia. 1973 Sep:320-30. doi: 10.1007/BF01218442.
2
Pharmacokinetics of glipizide in man: influence of renal insufficiency.
Diabetologia. 1973 Sep:331-8. doi: 10.1007/BF01218443.
3
[Changes in blood glucose and insulin in 4 normal subjects after administration of a single dose of glipizide and glibenclamide].[4名正常受试者单次服用格列吡嗪和格列本脲后血糖和胰岛素的变化]
Minerva Med. 1974 Jan 6;65(1):58-9.
4
Pharmacodynamic aspects of two sulphonylurea derivatives glipizide and glibenclamide.两种磺酰脲衍生物格列吡嗪和格列本脲的药效学方面
Diabetologia. 1973 Sep:311-6. doi: 10.1007/BF01218440.
5
Metabolism and kinetics of the hypoglycemic agent glipizide in man--comparison with glibenclamide.
J Clin Pharmacol New Drugs. 1973 Feb-Mar;13(2):68-75. doi: 10.1002/j.1552-4604.1973.tb00255.x.
6
Unaltered glucagon secretion after seven days of sulphonylurea administration in normal subjects.正常受试者服用磺脲类药物七天后胰高血糖素分泌未受影响。
Diabetologia. 1973 Sep:317-9. doi: 10.1007/BF01218441.
7
Clinical study with glipizide, a new oral antidiabetic drug.新型口服抗糖尿病药物格列吡嗪的临床研究。
Diabetologia. 1973 Sep:348-50. doi: 10.1007/BF01218445.
8
Glipizide, a new oral antidiabetic agent (report of a controlled clinical study in Sweden).格列吡嗪，一种新型口服抗糖尿病药物（瑞典一项对照临床研究报告）
Diabetologia. 1973 Sep:339-47. doi: 10.1007/BF01218444.
9
Effect of glipizide on a double-meal test in diabetic patients.
Arzneimittelforschung. 1972 Nov;22(11):1888-9.
10
A clinical study of the metabolic effect of a new oral hypoglycemic agent: glipizide.一种新型口服降糖药格列吡嗪代谢效应的临床研究。
Int J Clin Pharmacol. 1974 Apr;7(3):225-31.

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Investigation of Biotransformation Pathways in a Chimeric Mouse with a Humanized Liver.具有人源化肝脏的嵌合小鼠生物转化途径的研究
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A physiologically based pharmacokinetic model to predict the pharmacokinetics of highly protein-bound drugs and the impact of errors in plasma protein binding.一种基于生理学的药代动力学模型，用于预测高蛋白结合药物的药代动力学以及血浆蛋白结合误差的影响。
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3
Bioavailability of immediate- and extended-release formulations of glipizide in healthy male volunteers.

本文引用的文献

1
[Clinical experience concerning the action of a new oral antidiabetic drug: glidiazinamide].
Minerva Med. 1971 Jul 21;62(57):2829-39.
2
New oral antidiabetic drugs. 3.新型口服抗糖尿病药物。3.
Arzneimittelforschung. 1972 Mar;22(3):542-4.
3
Metabolism of glipizide in the rat and dog and its tissue distribution in the mouse.
Arzneimittelforschung. 1973 Feb;23(2):242-7.
4
格列吡嗪速释和缓释制剂在健康男性志愿者中的生物利用度。
Clin Pharmacokinet. 2006;45(3):317-24. doi: 10.2165/00003088-200645030-00007.
4
Pharmacokinetics of oral antihyperglycaemic agents in patients with renal insufficiency.肾功能不全患者口服降糖药的药代动力学
Clin Pharmacokinet. 1996 Aug;31(2):111-9. doi: 10.2165/00003088-199631020-00003.
5
Radioimmunoassay of glipizide in human plasma.
Eur J Clin Pharmacol. 1981;21(3):251-5. doi: 10.1007/BF00627928.
6
Clinical pharmacology of sulphonylurea hypoglycaemic agents: part 2.磺酰脲类降糖药的临床药理学：第2部分。
Drugs. 1981 Oct;22(4):295-320. doi: 10.2165/00003495-198122040-00003.
7
Clinical pharmacokinetics of sulphonylurea hypoglycaemic drugs.磺酰脲类降糖药物的临床药代动力学
Clin Pharmacokinet. 1981 May-Jun;6(3):215-41. doi: 10.2165/00003088-198106030-00003.
8
Glipizide versus tolbutamide, an open trial. Effects on insulin secretory patterns and glucose concentrations.格列吡嗪与甲苯磺丁脲对比：一项开放性试验。对胰岛素分泌模式和血糖浓度的影响。
Diabetologia. 1980 Jan;18(1):49-54. doi: 10.1007/BF01228302.
9
Glipizide, a new oral antidiabetic agent (report of a controlled clinical study in Sweden).格列吡嗪，一种新型口服抗糖尿病药物（瑞典一项对照临床研究报告）
Diabetologia. 1973 Sep:339-47. doi: 10.1007/BF01218444.
10
The relationship between the pharmacokinetics and pharmacodynamic effects of oral hypoglycaemic drugs.口服降糖药的药代动力学与药效学效应之间的关系。
Clin Pharmacokinet. 1987 Jun;12(6):379-401. doi: 10.2165/00003088-198712060-00001.
Effect of glipizide on a double-meal test in diabetic patients.
Arzneimittelforschung. 1972 Nov;22(11):1888-9.
5
Modifications of glycemia and insulinemia in diabetics treated with glipizide (K 4024), a new sulfonylurea.
Arzneimittelforschung. 1972 Nov;22(11):1885-8.
6
Clinical and metabolic observations with a new synthetic oral antidiabetic agent, glipizide.
Arzneimittelforschung. 1972 Nov;22(11):1879-81.
7
A controlled clinical trial of a new oral hypoglycemic agent, glipizide (K 4024).新型口服降糖药格列吡嗪（K 4024）的对照临床试验。
Arzneimittelforschung. 1972 Jul;22(7):1169-73.
8
[Studies on the bioavailability of glibenclamide].[格列本脲生物利用度的研究]
Arzneimittelforschung. 1972 Feb;22(2):471-3.
9
Glipizide, a new sulfonylurea in the treatment of diabetes mellitus. Summary of clinical experience in 1064 cases.格列吡嗪，一种治疗糖尿病的新型磺脲类药物。1064例临床经验总结。
Arzneimittelforschung. 1972 Nov;22(11):1881-5.