Werczberger A, Golhman J, Wertheim G, Gunders A E, Chowers I
Chest. 1979 Oct;76(4):482-4. doi: 10.1378/chest.76.4.482.
A 46-year-old man, who was twice operated on for echinococcosis and who suffered from recurrent angioneurotic edema, was hospitalized with anaphylactic shock. Chest x-ray examination showed round lesions in the lungs; Casoni, immunofluorescence and hemagglutination tests for echinococcosis were strongly positive. With a diagnosis of disseminated echinococcosis, drug treatment with mebenzadole was given for 29 weeks (the last 22 weeks a dose of 1,200 mg daily). No side effects were observed, allergic manifestations disappeared, and the round lesions were noticeably reduced. The titer of hemagglutination fell gradually, and IgE concentration initially increased and later fell. Mebendazole is proposed as a drug of choice in the cure of disseminated hydatidosis; it may both alter the indication for operation and considerably improve the prognosis.
一名46岁男性，曾因棘球蚴病接受过两次手术，患有复发性血管神经性水肿，因过敏性休克住院。胸部X线检查显示肺部有圆形病灶；棘球蚴病的卡索尼试验、免疫荧光试验和血凝试验均呈强阳性。诊断为播散性棘球蚴病后，给予甲苯达唑药物治疗29周（最后22周每日剂量为1200毫克）。未观察到副作用，过敏表现消失，圆形病灶明显缩小。血凝滴度逐渐下降，IgE浓度最初升高，随后下降。甲苯达唑被推荐为治疗播散性包虫病的首选药物；它既可能改变手术指征，又能显著改善预后。
