Rosen A D
Epilepsia. 1979 Aug;20(4):387-93. doi: 10.1111/j.1528-1157.1979.tb04818.x.
The influence of cerebral cortex on penicillin-induced spikes in striate cortex was studied with the technique of hypothermic block. Direct cooling of the involved or contralateral striate cortex markedly reduced seizure activity. Significant reduction in seizure activity was also seen with cooling of ipsilateral and contralateral visual association cortex. None of the other cortical areas tested had a reproducible effect on the frequency of seizures. These findings are discussed in term of local and remote factors influencing the epileptogenic focus.
采用低温阻断技术研究了大脑皮层对青霉素诱发的纹状皮层棘波的影响。直接冷却受累或对侧纹状皮层可显著降低癫痫发作活动。冷却同侧和对侧视觉联合皮层也可显著降低癫痫发作活动。所测试的其他皮层区域对癫痫发作频率均无重复性影响。根据影响致痫灶的局部和远处因素对这些发现进行了讨论。
