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[人离体平滑肌器官过敏反应的重现及几种肾上腺素能物质的作用]

[Reproduction of the anaphylactic reaction of isolated human smooth muscle organs and the effect of several adrenotropic substances].

作者信息

Poriadin G V, Baranov A P

出版信息

Biull Eksp Biol Med. 1975 Mar;79(3):76-9.

PMID:47769
Abstract

A comparative study was carried out of passive sensitization of the lungs, bronchi, small and large intestine by the blood sera of patients sensitive to ambrosia pollen. Passive sensitization and subsequent anaphylactic contraction were reproduced on the isolated bronchi, lungs and the ileum. Development of this reaction was less constant in the large intestine, jejunum and the appendix. The value of anaphylactic reaction of human smooth muscle displayed significant changes with the treatment of the muscles by agents selectively acting on the beta-adrenergic receptors of these organs.

摘要

对豚草花粉敏感患者的血清引起的肺、支气管、小肠和大肠的被动致敏进行了一项比较研究。在离体支气管、肺和回肠上再现了被动致敏及随后的过敏收缩。在大肠、空肠和阑尾中,这种反应的发展不太稳定。用选择性作用于这些器官β-肾上腺素能受体的药物处理肌肉后,人体平滑肌过敏反应的值发生了显著变化。

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