[3H]-蛋氨酸脑啡肽、[3H]-纳曲酮和[3H]-二氢吗啡在小鼠输精管、豚鼠肠肌丛和脑中的结合比较。

Comparison of binding of [3H]-methionine-enkephalin, [3H]-naltrexone and [3H]-dihydromorphine in the mouse vas deferens and the myenteric plexus and brain of the ginea pig.

作者信息

Leslie F M, Kosterlitz H W

出版信息

Eur J Pharmacol. 1979 Jul 1;56(4):379-83. doi: 10.1016/0014-2999(79)90269-3.

Abstract

[3H]-Methionine-enkephalin, [3H]-naltrexone and [3H]-dihydromorphine are specifically bound in homogenates of not only the brain and myenteric plexus of the guinea pig but also the vas deferens of the mouse. Brain has a ratio of methionine-enkephalin to dihydromorphine binding in favour of methionine-enkephalin binding and the myenteric plexus a ratio in favour of dihydromorphine binding, with the mouse vas deferens being intermediate.

摘要

[3H] - 蛋氨酸脑啡肽、[3H] - 纳曲酮和[3H] - 二氢吗啡不仅在豚鼠的脑和肠肌丛匀浆中，而且在小鼠的输精管中都有特异性结合。脑内蛋氨酸脑啡肽与二氢吗啡的结合比例有利于蛋氨酸脑啡肽的结合，而肠肌丛的比例则有利于二氢吗啡的结合，小鼠输精管的情况则介于两者之间。