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新生犊牛低血糖期间的脑氨生成

Cerebral ammonia production during hypoglycemia in the newborn calf.

作者信息

Gardiner R M, Wessel J N

出版信息

Experientia. 1979 Jul 15;35(7):872-3. doi: 10.1007/BF01955120.

DOI:10.1007/BF01955120
PMID:477834
Abstract

The effect of insulin hypoglycaemia on cerebral blood flow, and cerebral metabolic rates of glucose, oxygen and ammonia was investigated in the unanaesthetized newborn calf. A net loss of ammonia from the brain occurred during hypoglycaemia, and was greater in convulsing than in comatose animals.

摘要

在未麻醉的新生小牛中研究了胰岛素低血糖对脑血流量、脑葡萄糖、氧和氨代谢率的影响。低血糖期间脑内氨出现净损失,惊厥动物的氨净损失大于昏迷动物。

相似文献

1
Cerebral ammonia production during hypoglycemia in the newborn calf.新生犊牛低血糖期间的脑氨生成
Experientia. 1979 Jul 15;35(7):872-3. doi: 10.1007/BF01955120.
2
The effects of hypoglycaemia on cerebral blood flow and metabolism in the new-born calf.低血糖对新生犊牛脑血流量和代谢的影响。
J Physiol. 1980 Jan;298:37-51. doi: 10.1113/jphysiol.1980.sp013065.
3
Cerebral metabolic response and mitochondrial activity following insulin-induced hypoglycemia in newborn lambs.新生羔羊胰岛素诱导低血糖后的脑代谢反应和线粒体活性
Biol Neonate. 1989;55(4-5):281-9. doi: 10.1159/000242930.
4
Cerebral metabolic changes in profound, insulin-induced hypoglycemia, and in the recovery period following glucose administration.
J Neurochem. 1978 Nov;31(5):1135-42. doi: 10.1111/j.1471-4159.1978.tb06236.x.
5
Cerebral blood flow and metabolism during hypoglycaemia in the calf [proceedings].
J Physiol. 1979 Apr;289:46P.
6
Cerebral oxidative metabolism and blood flow during acute hypoglycemia and recovery in unanesthetized rats.
J Neurochem. 1982 Feb;38(2):397-409. doi: 10.1111/j.1471-4159.1982.tb08643.x.
7
Endogenous substrates utilized by rat brain in severe insulin-induced hypoglycemia.
J Neurochem. 1981 Feb;36(2):490-500. doi: 10.1111/j.1471-4159.1981.tb01619.x.
8
Influence of severe hypoglycemia on mitochondrial and plasma membrane function in rat brain.严重低血糖对大鼠脑线粒体和质膜功能的影响。
J Neurochem. 1982 Mar;38(3):662-8. doi: 10.1111/j.1471-4159.1982.tb08682.x.
9
Cerebral glucose transport and oxygen consumption in sheep and rabbits.绵羊和兔子的脑葡萄糖转运与氧消耗
J Physiol. 1973 Sep;233(3):529-51. doi: 10.1113/jphysiol.1973.sp010322.
10
Insulin hypoglycemia, cerebral metabolism, and neural function in fetal lambs.
Am J Physiol. 1985 Jan;248(1 Pt 2):R72-7. doi: 10.1152/ajpregu.1985.248.1.R72.

本文引用的文献

1
Studies on brain metabolism: The metabolism of glutamic acid in brain.脑代谢研究:脑中谷氨酸的代谢。
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2
SIMPLE METHODS FOR THE DETERMINATION OF THE CONCENTRATIONS OF CARBON DIOXIDE AND OXYGEN IN BLOOD.测定血液中二氧化碳和氧气浓度的简单方法。
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Hydrogen method for determining cerebral blood flow in man.
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Chemical changes in the brain during insulin hypoglycaemia and recovery.胰岛素低血糖及恢复过程中大脑的化学变化。
J Neurochem. 1965 Aug;12(8):679-93. doi: 10.1111/j.1471-4159.1965.tb06782.x.
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Amino acid metabolism and ammonia formation in brain slices.脑切片中的氨基酸代谢与氨生成
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6
Brain amino acids during convulsions.惊厥期间的脑氨基酸
J Neurochem. 1974 Feb;22(2):307-9. doi: 10.1111/j.1471-4159.1974.tb11595.x.
7
[Direct determination of plasma ammonia without deproteinization. An improved enzymic determination of ammonia, II (author's transl)].[无需去蛋白直接测定血浆氨。氨的一种改进酶法测定,II(作者译)]
Z Klin Chem Klin Biochem. 1973 Oct;11(10):426-31.
8
Changes in carbohydrate substrates, amino acids and ammonia in the brain during insulin-induced hypoglycemia.胰岛素诱导的低血糖期间大脑中碳水化合物底物、氨基酸和氨的变化。
J Neurochem. 1974 Oct;23(4):659-71. doi: 10.1111/j.1471-4159.1974.tb04389.x.