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无蛋白甲状旁腺提取物对大鼠骨髓细胞有丝分裂指数的辐射防护作用。

Radioprotective effect of a protein free parathyroid extract on the mitotic index of rat bone marrow cells.

作者信息

Feuer L, Ormai S

出版信息

Experientia. 1979 Aug 15;35(8):1091-2. doi: 10.1007/BF01949961.

DOI:10.1007/BF01949961
PMID:477889
Abstract

The protective efficacy of an orally administered bovine protein-free parathyroid extract (PF-PTE) was studied on rat bone marrow cells in vivo with the mitotic index after 850 R irradiation. A remarkable decrease was found in the mitotic activity of bone marrow cells after irradiation in the non-protected animals. However, in the animals treated with PF-PTE after irradiation, a significantly smaller decrease and a faster recovery were found in the mitotic activity of the bone marrow cells.

摘要

采用850伦琴照射后有丝分裂指数，对口服无牛蛋白甲状旁腺提取物（PF-PTE）在体内对大鼠骨髓细胞的保护功效进行了研究。在未受保护的动物中，照射后骨髓细胞的有丝分裂活性显著下降。然而，在照射后用PF-PTE治疗的动物中，骨髓细胞的有丝分裂活性下降明显较小且恢复更快。

相似文献

1
Radioprotective effect of a protein free parathyroid extract on the mitotic index of rat bone marrow cells.无蛋白甲状旁腺提取物对大鼠骨髓细胞有丝分裂指数的辐射防护作用。
Experientia. 1979 Aug 15;35(8):1091-2. doi: 10.1007/BF01949961.
2
Comparison of the protective action of glutathione and cysteamine on radiation-induced mitotic delay in cultured S-5 cells.谷胱甘肽和半胱胺对培养的S-5细胞辐射诱导的有丝分裂延迟的保护作用比较。
Radiology. 1979 Jun;131(3):759-62. doi: 10.1148/131.3.759.
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[Effect of different X-ray radiation dosage on the development of chromosomal aberrations and rate of their elimination from bone marrow cells in mice. I. Mitotic index].[不同X射线辐射剂量对小鼠骨髓细胞染色体畸变发生及消除率的影响。I. 有丝分裂指数]
Rocz Panstw Zakl Hig. 1978;29(5):567-74.
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本文引用的文献

1
Radioprotective efficacy of cysteamine with the mitotic index of rat bone marrow cells as reference system.以大鼠骨髓细胞有丝分裂指数为参照体系的半胱胺辐射防护效能
Acta Radiol (Stockh). 1961 Nov;56:393-8. doi: 10.3109/00016926109172834.
2
Influence of protein free aqueous extract of parathyroid powder on serum vitamin A level in rats.甲状旁腺粉无蛋白水提取物对大鼠血清维生素A水平的影响。
Experientia. 1977 Aug 15;33(8):1005-6. doi: 10.1007/BF01945934.
3
Radioprotective effect of a protein free parathyroid extract.
Experientia. 1978 Oct 15;34(10):1356-7. doi: 10.1007/BF01981469.