Wolf A, Vahrson H, Hoss M
Geburtshilfe Frauenheilkd. 1979 Jun;39(6):497-502.
The determination of the plasmaribonucleases was reported by Sheid and co-workers in 1977 for the diagnosis of carcinoma of the ovary. The authors investigated the accuracy of this test with a modified method in a double blind study encompassing healthy controls. Blood samples from 62 patients with ovarian cancer were tested. The results were accurate in 56 cases. In 6 cases the test results were doubtful. The difference in the ribonuclease activity was significant between patients with ovarian cancer and healthy patients or patients in remission from ovarian cancer. The results were not dependant upon the FIGO staging of the disease. Our results encourage the recommendation to use this test as a diagnostic aid in carcinoma of the ovary.
1977年，谢德及其同事报告了血浆核糖核酸酶的测定用于卵巢癌的诊断。作者在一项包含健康对照的双盲研究中，用改良方法研究了该检测的准确性。对62例卵巢癌患者的血样进行了检测。56例结果准确，6例结果可疑。卵巢癌患者与健康患者或卵巢癌缓解期患者之间的核糖核酸酶活性差异显著。结果不取决于疾病的国际妇产科联盟（FIGO）分期。我们的结果促使推荐将该检测用作卵巢癌的诊断辅助手段。
