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[麻风反应患者尺神经的运动传导速度。沙利度胺治疗期间13年观察系列总结]

[Motor-conduction velocity of cubital nerves in patients with leprosy reactions. Summary of a 13-year observation series during thalidomide therapy].

作者信息

Sheskin J, Yaar I

出版信息

Hautarzt. 1979 Jul;30(7):376-9.

PMID:478858
Abstract

The motor conduction velocity of the ulnar nerves was examined repeatedly in 34 patients with lepromatous leprosy. In patients with active lesions the reduction in velocity paralleled clinical deterioration. In "burned-out" control patients, who had never suffered from leprosy reaction, the conduction velocity remained slow and unchanged over many years. Twenty-six of 34 patients suffering from leprosy reaction received Thalidomide treatment over a period of 6-13 years in order to suppress the reaction, with good effect. In none of these 26 patients neurotoxic disturbances were found.

摘要

对34例瘤型麻风患者的尺神经运动传导速度进行了反复检测。在有活动性病变的患者中,神经传导速度的降低与临床病情恶化情况平行。在从未发生过麻风反应的“静止期”对照患者中,多年来神经传导速度一直缓慢且无变化。34例发生麻风反应的患者中有26例接受了为期6至13年的沙利度胺治疗以抑制反应,效果良好。在这26例患者中均未发现神经毒性障碍。

相似文献

1
[Motor-conduction velocity of cubital nerves in patients with leprosy reactions. Summary of a 13-year observation series during thalidomide therapy].[麻风反应患者尺神经的运动传导速度。沙利度胺治疗期间13年观察系列总结]
Hautarzt. 1979 Jul;30(7):376-9.
2
Five years' experience with thalidomide treatment in leprosy reaction.
Int J Lepr Other Mycobact Dis. 1971 Apr-Jun;39(2):585-8.
3
The condition of the peripheral nerve in leprosy under various forms of treatment. Conduction velocity studies in long-term follow-up.
Int J Lepr Other Mycobact Dis. 1971 Apr-Jun;39(2):639-52.
4
Motor conduction velocity studies in patients with leprosy reaction treated with thalidomide and other drugs.对接受沙利度胺及其他药物治疗的麻风反应患者进行运动神经传导速度研究。
Int J Lepr Other Mycobact Dis. 1969 Oct-Dec;37(4):359-64.
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[Therapeutic experience on the effect of thalidomidomide on lepra reaction].沙利度胺治疗麻风反应疗效的治疗经验
Hautarzt. 1975 Jan;26(1):1-5.
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Effect of drug treatment on electroneurological measures of peripheral nerve function in leprosy patients.药物治疗对麻风病患者周围神经功能电神经学指标的影响。
Ceylon Med J. 1993 Dec;38(4):174-7.
7
Controlled follow-up assessment of the effect of thalidomide upon the ulnar nerve in leprosy.
Int J Lepr Other Mycobact Dis. 1971 Oct-Dec;39(4):863-71.
8
The condition of the peripheral nerve in leprosy under various forms of treatment. Conduction velocity studies in long-term follow-up.
Int J Lepr Other Mycobact Dis. 1970 Apr-Jun;38(2):149-63.
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Motor nerve conduction velocity studies of the ulnar nerve in patients with leprosy.麻风病患者尺神经的运动神经传导速度研究。
Int J Lepr Other Mycobact Dis. 1968 Jul-Sep;36(3):282-7.
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Nerve conduction in leprosy: in vivo and in vitro study.
Lepr India. 1983 Jan;55(1):12-21.

引用本文的文献

1
Thalidomide-induced peripheral neuropathy. A prospective clinical, neurophysiological and pharmacogenetic evaluation.沙利度胺所致周围神经病变。一项前瞻性临床、神经生理学及药物遗传学评估。
J Neurol. 1986 Apr;233(2):83-9. doi: 10.1007/BF00313852.
2
Thalidomide in human immunodeficiency virus (HIV) patients. A review of safety considerations.沙利度胺用于人类免疫缺陷病毒(HIV)患者。安全性考量综述。
Drug Saf. 1992 Mar-Apr;7(2):116-34. doi: 10.2165/00002018-199207020-00004.