Sheskin J, Yaar I
Hautarzt. 1979 Jul;30(7):376-9.
The motor conduction velocity of the ulnar nerves was examined repeatedly in 34 patients with lepromatous leprosy. In patients with active lesions the reduction in velocity paralleled clinical deterioration. In "burned-out" control patients, who had never suffered from leprosy reaction, the conduction velocity remained slow and unchanged over many years. Twenty-six of 34 patients suffering from leprosy reaction received Thalidomide treatment over a period of 6-13 years in order to suppress the reaction, with good effect. In none of these 26 patients neurotoxic disturbances were found.
对34例瘤型麻风患者的尺神经运动传导速度进行了反复检测。在有活动性病变的患者中,神经传导速度的降低与临床病情恶化情况平行。在从未发生过麻风反应的“静止期”对照患者中,多年来神经传导速度一直缓慢且无变化。34例发生麻风反应的患者中有26例接受了为期6至13年的沙利度胺治疗以抑制反应,效果良好。在这26例患者中均未发现神经毒性障碍。