Forsling M L, Taverne M A, Parvizi N, Elsaesser F, Smidt D, Ellendorff F
J Endocrinol. 1979 Jul;82(1):61-9. doi: 10.1677/joe.0.0820061.
Plasma oxytocin concentrations were measured during late pregnancy, parturition and lactation in the miniature pig. Measurements were made of plasma oestradiol, oestrone and progesterone to determine whether there was any relationship between the concentrations of oxytocin and these steroids in the circulation. Plasma oxytocin concentrations were low or undetectable in late pregnancy. Rises of up to 68.8 mum./ml were seen at the time of delivery of the foetuses and at the expulsion of the placenta. The only steroid that seemed to relat to oxytocin release was progesterone. Oxytocin release was consistently seen when progesterone concentrations had fallen to below 10 ng/ml but no increase in concentration was observed while oestrone and oestradiol increased to their maximum concentrations of 3.86--11.6 and 0.43--0.70 ng/ml respectively. During lactation, when both oestrogen and progesterone concentrations were low, suckling caused the levels of oxytocin to increase to 7.4 muu./ml. These increases were greater during the first 2 weeks of lactation than later.
在小型猪的妊娠晚期、分娩期和哺乳期测量了血浆催产素浓度。同时测量了血浆雌二醇、雌酮和孕酮，以确定循环中催产素浓度与这些类固醇之间是否存在任何关系。妊娠晚期血浆催产素浓度较低或无法检测到。在胎儿分娩时和胎盘排出时，血浆催产素浓度升高高达68.8毫微克/毫升。唯一似乎与催产素释放有关的类固醇是孕酮。当孕酮浓度降至10纳克/毫升以下时，始终会出现催产素释放，但当雌酮和雌二醇分别升至其最高浓度3.86 - 11.6纳克/毫升和0.43 - 0.70纳克/毫升时，未观察到浓度增加。在哺乳期，当雌激素和孕酮浓度都较低时，哺乳会使催产素水平增加至7.4毫微克/毫升。这些增加在哺乳期的前两周比后期更大。
