Tuma A H, May P R
J Nerv Ment Dis. 1979 Sep;167(9):566-71. doi: 10.1097/00005053-197909000-00008.
A systematic study of schizophrenic patients who did not respond satisfactorily to one of five different forms of treatment given under controlled conditions showed that almost all of them responded satisfactorily to subsequent treatment with the combination of ataraxic drugs and group psychotherapy. Whatever the original form of treatment, and despite subsequent retreatment with drugs and group psychotherapy, there was a treatment-resistant core--a few patients who either responded very slowly or who improved relatively little.
对在受控条件下接受五种不同治疗形式之一但反应不令人满意的精神分裂症患者进行的一项系统研究表明，几乎所有患者随后接受镇静药物与集体心理治疗相结合的治疗时反应都令人满意。无论最初的治疗形式如何，且尽管随后再次接受药物和集体心理治疗，仍有一个对治疗有抵抗的核心——少数患者要么反应非常缓慢，要么改善相对较小。
