Holland R I
J Inorg Biochem. 1979 Aug;11(1):1-6. doi: 10.1016/s0162-0134(00)80047-1.
Uptake of 51Cr-chromate by freshly collected human erythrocytes was inhibited by 90 mM sodium fluoride only in cells preincubated with fluoride. In vitro storage also increased the sensitivity of the cells: 90 mM NaF clearly inhibited the uptake of chromate in cells stored in vitro for 5 weeks. Gel chromatography revealed two forms of 51Cr within the cells, one of small molecular weight, which thin layer chromatography indicated was unchanged chromate; the other form was apparently bound to macromolecules such as hemoglobin.
仅在预先用氟化物孵育的细胞中，90 mM 氟化钠可抑制新鲜采集的人红细胞对 51Cr-铬酸盐的摄取。体外储存也增加了细胞的敏感性：90 mM NaF 明显抑制了体外储存 5 周的细胞中铬酸盐的摄取。凝胶色谱显示细胞内有两种 51Cr 形式，一种是小分子质量的，薄层色谱表明是未变化的铬酸盐；另一种形式显然与血红蛋白等大分子结合。
