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Characterisation of cytochrome P-450 species in rat liver microsomes, I. Differences in the O-dealkylation of 7-ethoxycoumarin after pretreatment with phenobarbital and 3-methylcholanthrene.

作者信息

Ullrich V, Frommer U, Weber P

出版信息

Hoppe Seylers Z Physiol Chem. 1973 May;354(5):514-20. doi: 10.1515/bchm2.1973.354.1.514.

DOI:10.1515/bchm2.1973.354.1.514
PMID:4803489
Abstract
摘要

相似文献

1
Characterisation of cytochrome P-450 species in rat liver microsomes, I. Differences in the O-dealkylation of 7-ethoxycoumarin after pretreatment with phenobarbital and 3-methylcholanthrene.大鼠肝脏微粒体中细胞色素P - 450种类的表征，I. 苯巴比妥和3 - 甲基胆蒽预处理后7 - 乙氧基香豆素O - 脱烷基作用的差异
Hoppe Seylers Z Physiol Chem. 1973 May;354(5):514-20. doi: 10.1515/bchm2.1973.354.1.514.
2
Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene.乙氧芴羟香豆素：一种微粒体O-脱烷基化反应的直接荧光测定法，该反应优先被3-甲基胆蒽诱导。
Drug Metab Dispos. 1974 Nov-Dec;2(6):583-8.
3
Hydroperoxide catalyzed liver microsomal aromatic hydroxylation reactions involving cytochrome P-450.
Biochem Biophys Res Commun. 1974 Sep 9;60(1):440-7. doi: 10.1016/0006-291x(74)90223-x.
4
Comparison of trans-stilbene oxide, phenobarbital and 3-methylcholanthrene as inducers of steroid metabolism by the rat liver microsomal cytochrome P-450 system.反式氧化茋、苯巴比妥和3-甲基胆蒽作为大鼠肝脏微粒体细胞色素P-450系统甾体代谢诱导剂的比较。
J Steroid Biochem. 1983 Apr;18(4):425-35. doi: 10.1016/0022-4731(83)90061-4.
5
Effects of phenobarbital and 3-methylcholanthrene on the hepatic cytochrome P-450 metabolism of various alkoxyresorufin ethers in the cotton rat (Sigmodon hispidus).苯巴比妥和3-甲基胆蒽对棉鼠（刚毛棉鼠）肝脏中细胞色素P-450代谢各种烷氧基试卤灵醚的影响。
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1989;94(2):543-5. doi: 10.1016/0742-8413(89)90110-2.
6
Tetrahydrofurane - an inhibitor for ethanol-induced liver microsomal cytochrome P450.四氢呋喃——一种乙醇诱导的肝微粒体细胞色素P450的抑制剂。
Biochem Biophys Res Commun. 1975 Jan 2;64(3):808-13. doi: 10.1016/0006-291x(75)90119-9.
7
Effect of phenobarbital and 3-methylcholanthrene administration in vivo and isooctane extraction in vitro on metyrapone binding to reduced cytochrome P-450.
Biochem Pharmacol. 1974 Aug 15;23(16):2305-14. doi: 10.1016/0006-2952(74)90559-0.
8
Comparison of the drug metabolising ability of rat intestinal mucosal microsomes with that of liver.大鼠肠黏膜微粒体与肝脏药物代谢能力的比较。
Biochem Pharmacol. 1979 Sep 15;28(18):2835-9. doi: 10.1016/0006-2952(79)90569-0.
9
Reconstituted O-dealkylase systems containing various forms of liver microsomal cytochrome P-450.含有各种形式肝脏微粒体细胞色素P-450的重组O-脱烷基酶系统。
J Biochem. 1979 Dec;86(6):1697-707. doi: 10.1093/oxfordjournals.jbchem.a132690.
10
Differences in P-450 cytochromes from livers of rats treated with phenobarbital and with 3-methylcholanthrene.用苯巴比妥和3-甲基胆蒽处理的大鼠肝脏中细胞色素P-450的差异。
J Biol Chem. 1973 Mar 25;248(6):2192-201.

引用本文的文献

1
Involvement of mixed function oxidase systems in polychlorinated biphenyl metabolism by plant cells.植物细胞中环氯联苯代谢中混合功能氧化酶系统的作用。
Plant Cell Rep. 1992 Mar;11(2):97-100. doi: 10.1007/BF00235262.
2
Non-linear kinetics of microsomal styrene monooxygenase after phenobarbital pre-treatment.
Experientia. 1980 Jun 15;36(6):640-1. doi: 10.1007/BF01970108.
3
7-Ethoxycoumarin deethylation in rainbow trout (Salmo gairdneri).虹鳟（萨氏虹鳟）体内7-乙氧基香豆素的脱乙基作用
Bull Environ Contam Toxicol. 1982 Oct;29(4):492-7. doi: 10.1007/BF01605617.
4
Polychlorinated biphenyls (Aroclors 1016 and 1242): effect on hepatic microsomal mixed function oxidases in mink and ferrets.多氯联苯（Aroclors 1016和1242）：对水貂和雪貂肝脏微粒体混合功能氧化酶的影响。
Arch Environ Contam Toxicol. 1982;11(3):313-21. doi: 10.1007/BF01055208.
5
Dinemorphan N-demethylation by mouse liver microsomes.
Experientia. 1984 Feb 15;40(2):180-2. doi: 10.1007/BF01963588.
6
Cytochrome P-450-dependent production of chemotactic arachidonate metabolites from human neutrophils.细胞色素P-450介导的人中性粒细胞趋化性花生四烯酸代谢物的生成。
Arch Dermatol Res. 1984;276(4):243-5. doi: 10.1007/BF00414236.
7
Induction of cytochrome P-448 iso-enzymes and related glucuronyltransferases in the human liver by cigarette smoking.
Eur J Clin Pharmacol. 1986;30(4):475-80. doi: 10.1007/BF00607963.
8
3-Methylcholanthrene-induced ethoxyresorufin O-deethylase activity in alveolar type II cells of rabbit lung.
Arch Toxicol. 1986 May;59(1):1-3. doi: 10.1007/BF00263947.
9
[Long time HCB exposition of rats: influence on the porphyrin excretion in the urine and on the cytochrome P-450 in the liver (author's transl)].
Arch Dermatol Res (1975). 1977 Aug 22;259(2):199-206. doi: 10.1007/BF00557961.
10
[Hexachlorbenzene (HCB) induced porphyria in rats. Influence of HCB-metabolites on the biosynthesis of heme (author's transl)].[六氯苯（HCB）诱导大鼠卟啉症。HCB代谢产物对血红素生物合成的影响（作者译）]
Arch Dermatol Res. 1978 Nov 10;263(2):189-96. doi: 10.1007/BF00446440.