Thomas P
Postgrad Med J. 1973 May;49(571):349-54. doi: 10.1136/pgmj.49.571.349.
The occurrence of carcinoma in the stomach and dysimmunoglobulinaemia in a patient who had Sjögren's syndrome is described. This is believed to be the first report of such a case to be found in the literature. Although carcinoma has occasionally been described, in this syndrome its occurrence is probably coincidental and not part of the disease process. There is a greater incidence of lymphoid tumours in Sjögren's syndrome than in the general population. Corticosteroid therapy favourably influenced the immunoglobulin abnormalities and some of the clinical manifestations of the disease. A brief review of the literature concerning Sjögren's syndrome, auto-immunity and malignant disease is included.
本文描述了一名患有干燥综合征的患者出现胃癌和免疫球蛋白异常血症的情况。据信这是文献中首次报道的此类病例。虽然偶尔有关于癌症的描述，但在该综合征中其发生可能是巧合，并非疾病过程的一部分。干燥综合征中淋巴瘤的发病率高于普通人群。皮质类固醇疗法对免疫球蛋白异常和该疾病的一些临床表现有积极影响。本文还包括了关于干燥综合征、自身免疫和恶性疾病的文献简要综述。
