• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

链球菌制剂（OK-432）治疗膀胱癌的免疫学评估

Immunological evaluation of a streptococcal preparation (OK-432) in treatment of bladder carcinoma.

作者信息

Kagawa S, Ogura K, Kurokawa K, Uyama K

出版信息

J Urol. 1979 Oct;122(4):467-70. doi: 10.1016/s0022-5347(17)56466-6.

DOI:10.1016/s0022-5347(17)56466-6
PMID:480487
Abstract

When 21 patients with bladder cancer (transitional cell carcinoma) were given local and systemic injections of a streptococcal preparation, OK-432, tumor regression was observed in 3 cases (14.3%). The marked infiltration of lymphocytes observed on histological examination of regressed tumors suggested that a host-mediated action was involved in the antitumor effect of OK-432.

摘要

当对21例膀胱癌（移行细胞癌）患者进行局部和全身注射链球菌制剂OK-432时，3例（14.3%）出现肿瘤消退。对消退肿瘤进行组织学检查时观察到明显的淋巴细胞浸润，提示宿主介导的作用参与了OK-432的抗肿瘤效应。

相似文献

1
Immunological evaluation of a streptococcal preparation (OK-432) in treatment of bladder carcinoma.链球菌制剂（OK-432）治疗膀胱癌的免疫学评估
J Urol. 1979 Oct;122(4):467-70. doi: 10.1016/s0022-5347(17)56466-6.
2
Evaluation of streptococcal preparation (OK-432) local injection in patients with urinary bladder carcinoma.膀胱肿瘤患者局部注射链球菌制剂（OK-432）的疗效评估
Osaka City Med J. 1980;26(1):47-59.
3
The role of adjunctive immunotherapy in superficial bladder cancer.辅助免疫疗法在浅表性膀胱癌中的作用。
Cancer. 1987 Jun 15;59(12):2027-30. doi: 10.1002/1097-0142(19870615)59:12<2027::aid-cncr2820591210>3.0.co;2-n.
4
Antigenic relationship between streptococcal preparation OK-432 and tumors and its effect on immunotherapy with OK-432 in patients with superficial bladder tumor.链球菌制剂OK-432与肿瘤之间的抗原关系及其对浅表性膀胱肿瘤患者使用OK-432进行免疫治疗的影响。
Urol Int. 1989;44(4):198-204. doi: 10.1159/000281504.
5
[Local immunotherapy with streptococcal preparation, OK-432 in superficial bladder tumors, and common antigens between OK-432 and the tumor].[浅表性膀胱肿瘤的链球菌制剂OK-432局部免疫疗法以及OK-432与肿瘤之间的共同抗原]
Hinyokika Kiyo. 1989 Feb;35(2):253-7.
6
Histological changes caused by intralesional injection of a streptococcal preparation into bladder cancer.通过向膀胱癌病灶内注射链球菌制剂所引起的组织学变化。
Cancer Detect Prev. 1988;11(3-6):397-403.
7
[An experience of OK-432 intradermal administration in superficial bladder tumors].[OK-432皮内注射治疗浅表性膀胱肿瘤的经验]
Hinyokika Kiyo. 1988 Dec;34(12):2111-4.
8
The streptococcal preparation OK-432 specifically augments the susceptibility of human urinary bladder tumor cells to autologous peripheral blood lymphocytes.链球菌制剂OK-432可特异性增强人膀胱肿瘤细胞对自体外周血淋巴细胞的敏感性。
Cancer. 1992 Jun 15;69(12):2999-3007. doi: 10.1002/1097-0142(19920615)69:12<2999::aid-cncr2820691223>3.0.co;2-a.
9
[Treatment of tumors of the urinary bladder with so-called immunopotentiators].
Hinyokika Kiyo. 1983 Jan;29(1):9-15.
10
[Thermotherapy for cancer of the urinary bladder in combination with tegafur suppository and picibanil--concentrations of tegafur in the serum and tissues in bladder carcinoma].
Gan To Kagaku Ryoho. 1985 May;12(5):1152-5.

引用本文的文献

1
Cytokine-mediated antitumor effect of OK-432 on urinary bladder tumor cells in vitro.OK-432对膀胱肿瘤细胞的细胞因子介导的体外抗肿瘤作用。
Urol Res. 1997;25(4):239-45. doi: 10.1007/BF00942092.
2
Keyhole-limpet haemocyanin (KLH) immunotherapy of murine transitional cell carcinoma.鼠移行细胞癌的匙孔血蓝蛋白（KLH）免疫疗法。
Urol Res. 1983;11(6):263-5. doi: 10.1007/BF00256343.
3
Combined therapeutic effects of an immunomodulator, PSK, and chemotherapy with carboquone on rat bladder carcinoma.免疫调节剂PSK与卡波醌联合化疗对大鼠膀胱癌的治疗效果
Cancer Chemother Pharmacol. 1985;15(1):54-8. doi: 10.1007/BF00257295.
4
Immunologic parameters in patients with thyroid cancer.甲状腺癌患者的免疫参数
Arch Otorhinolaryngol. 1986;243(2):91-5. doi: 10.1007/BF00453756.