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白质切断术对难治性青少年体重恐惧症(原发性神经性厌食症)的疗效。

The effect of leucotomy in intractable adolescent weight phobia (primary anorexia nervosa).

作者信息

Crisp A H, Kalucy R S

出版信息

Postgrad Med J. 1973 Dec;49(578):883-93. doi: 10.1136/pgmj.49.578.883.

Abstract

Anorexia nervosa is best construed as a phobic avoidance response to the psychosocial maturational implications of adolescent weight. Within this state, surrender to the impulse to eat and consequent weight gain is associated with panic, depression and sometimes specific intense fear of loss of control. So long as the avoidance posture can be maintained the experience of such turmoil is largely avoided. Complicated ritualistic behaviour may arise to promote and secure the posture. However, its unrewarding and lonely nature still increasingly leaves the individual liable to the experience of depression. Established treatment procedures often assist recovery from the illness but intractable cases arise and it is amongst these that the majority of deaths occur either from inanition or suicide. The basis for the changes characteristically induced by leucotomy is complex. The procedure often leads to reduced tension and release of appetitive behaviour. This is taken to be due to some direct effect of the cerebral lesion and possibly the intervention may also be construed by some patients as a licence to behave differently. In patients with anorexia nervosa such appetitive release can be expected to promote considerable weight gain. However, the adverse psychological implications of such weight gain for the patient do not appear always to be so immediately or easily relieved. They may still experience panic, shame or depression and new patterns of social avoidance, or vomiting behaviour may develop. Intensive help of a psychotherapeutic and rehabilitative kind is then still required if the patient is to have the best chance of adjusting healthily to her newly found potential for a more normal nutritional status. Four patients who have undergone such treatment are described in this paper. It is concluded that leucotomy has a small but definite place in the treatment of patients with intractable anorexia nervosa.

摘要

神经性厌食症最好被理解为对青少年体重所蕴含的心理社会成熟意义的一种恐惧回避反应。在这种状态下,屈服于进食冲动并随之体重增加会引发恐慌、抑郁,有时还会产生对失控的特定强烈恐惧。只要能维持回避姿态,这种混乱的体验在很大程度上就能避免。可能会出现复杂的仪式化行为来促进并确保这种姿态。然而,其徒劳且孤独的本质仍然越来越使个体易于陷入抑郁体验。既定的治疗程序通常有助于患者康复,但仍会出现难治性病例,而大多数死亡病例就出现在这些难治性病例中,死因要么是营养不良,要么是自杀。脑白质切断术引发的典型变化的基础很复杂。该手术常常会导致紧张感降低和食欲行为的释放。这被认为是由于脑部病变的某些直接影响,而且可能有些患者也会将这种干预理解为一种行为改变的许可。对于神经性厌食症患者,这种食欲释放预计会促使体重显著增加。然而,这种体重增加对患者产生的不良心理影响似乎并不总是能立即或轻易得到缓解。他们可能仍然会经历恐慌、羞耻或抑郁,并且可能会形成新的社交回避模式,或者出现呕吐行为。如果患者想要有最好的机会健康地适应其新发现的更正常营养状态的潜力,那么仍然需要强化的心理治疗和康复帮助。本文描述了四位接受过此类治疗的患者。得出的结论是,脑白质切断术在难治性神经性厌食症患者的治疗中占有小但明确的一席之地。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef6d/2495467/726bfbd710ec/postmedj00324-0096-a.jpg

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