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[氯化钾作用下牛颈动脉的碳水化合物代谢]

[Carbohydrate metabolism in the bovine carotid artery contracted by the action of potassium chloride].

作者信息

Laszlo M, Cappelli-Gotzos B, Conti G

出版信息

Arch Fisiol. 1973 Dec;70(3-4):167-76.

PMID:4807466
Abstract

The concentration of some end products and the activity of some enzymes participating in carbohydrates metabolism were examined in bovine carotid artery contracted by KCl. Oxygen consumption decreased significantly, anaerobic glycolysis and tissue lactic acid content increased during the KCl contraction. The hexosamines and the uronic acids producing ability of the KCl contracted artery were also higher. During contraction the SDH activity decreased in a smaller degree, cytochrome oxydase activity in a much more important degree. On the basis of our results we can conclude that the complete oxydation pathway of carbohydrates degradation, as mucopolysaccharides synthesis and degradation have an important part in the energy metabolism, but anaerobic glycolysis is the most important pathway to produce energy for the KCl contraction of vascular smooth muscle.

摘要

对氯化钾收缩的牛颈动脉中一些终产物的浓度以及参与碳水化合物代谢的一些酶的活性进行了检测。在氯化钾收缩过程中,耗氧量显著降低,无氧糖酵解和组织乳酸含量增加。氯化钾收缩的动脉中己糖胺和糖醛酸的生成能力也更高。收缩过程中,琥珀酸脱氢酶(SDH)活性下降程度较小,细胞色素氧化酶活性下降程度更为显著。根据我们的结果可以得出结论,碳水化合物降解的完全氧化途径,由于粘多糖的合成和降解在能量代谢中起重要作用,但无氧糖酵解是血管平滑肌氯化钾收缩产生能量的最重要途径。

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